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Head-to-head dispatch

LevelUp Rx vs Rylo Health

Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.

Dispatch #397
LevelUp Rx

LevelUp Rx is a telehealth pharmacy offering compounded GLP-1 weight-loss medications - compounded semaglutide and compounded tirzepatide - alongside a broad menu of men's and women's health treatments.

Marked down on: Compounded only - no brand-name Wegovy, Zepbound, Ozempic or Mounjaro

vs
Dispatch #100Desk pick
Rylo Health

Texas-prescriber telehealth selling compounded semaglutide and tirzepatide alongside a peptide line, naming both its medical group and its dispensing pharmacy.

Marked down on: Headline $100 and $160 rates are limited to the first 20 patients; standard rates are $149 and $249

Rylo Health takes this head-to-head with the higher Desk Score, 76/100 (C) against 53/100 (C) for LevelUp Rx. LevelUp Rx still holds its ground where its strengths line up with yours.

Desk Score, dimension by dimension

Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.

LevelUp Rx

53/100

C

Overall

Rylo Health

76/100

C

Price transparency

20
68

State access

24
86

Molecule range

72
72

Onboarding speed

83
82

Support responsiveness

76
79

Licensing & trust

84
75

The spec sheet

FieldLevelUp RxRylo Health
Semaglutide$150/mo (starting dose, compounded)$149/mo (promotional rate, compounded)
Tirzepatide$250/mo (starting dose, compounded)$249/mo (compounded)
CoverageCoverage not publishedAll 50 states
Brand-nameCompounded onlyCompounded only
Oral optionInjectable onlyInjectable only
Best forReaders who want compounded semaglutide and tirzepatide at a flat price with named pharmacies.Shoppers who want the pharmacy and medical group named before they buy.
Desk Score53/100C76/100C

The verdict

Desk pick — Rylo Health

Rylo Health takes this head-to-head with the higher Desk Score, 76/100 (C) against 53/100 (C) for LevelUp Rx. LevelUp Rx still holds its ground where its strengths line up with yours.

Choose LevelUp Rx if…

Readers who want compounded semaglutide and tirzepatide at a flat price with named pharmacies.

$150/mo (starting dose, compounded) sema · $250/mo (starting dose, compounded) tirz · Coverage not published

Choose Rylo Health if…

Shoppers who want the pharmacy and medical group named before they buy.

$149/mo (promotional rate, compounded) sema · $249/mo (compounded) tirz · All 50 states

Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: LevelUp Rx · Rylo Health.

Also here

CoreAge Rx tops every dispatch at 94/100

Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.

More head-to-heads

Or see the full comparison hub and the complete ranking.

Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.