Head-to-head comparison
Jyra Health vs NewSelf
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
Jyra Health is an online weight-loss and longevity telehealth clinic offering compounded GLP-1 — semaglutide from $99/mo and tirzepatide from $133/mo (limited time).
From $99/mo (lowest dose rung) sema · $133/mo (promo rate) tirz · Verified June 2026
Marked down on: The $133/mo tirzepatide price is flagged 'limited time' — verify current pricing before enrolling
Desk Score
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo).
$100/mo sema · $144/mo tirz · Verified July 2026
Marked down on: Not available in Mississippi and Louisiana
FDAWarning letter issued to NewSelf Limited dba NewSelf in February 2026. See the FDA warning-letter database.
NewSelf takes this head-to-head with the higher Desk Score, 79/100 (C+) against 75/100 (C) for Jyra Health. Jyra Health still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Jyra Health
75/100
C
NewSelf
79/100
C+
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Jyra Health | NewSelf |
|---|---|---|
| Semaglutide | From $99/molowest dose rung$99/mo (starting dose, plus a separate fee, compounded) | $100/mo$100/mo (compounded) |
| Tirzepatide | $133/mopromo rate$133/mo (starting dose, promotional rate, compounded) | $144/mo$144/mo (compounded) |
| Coverage | All 50 states | 49 states |
| Brand-name | Compounded only | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | Budget shoppers wanting very low-cost compounded semaglutide or tirzepatide in any state. | Lowest-cost compounded GLP-1 with pharmacy quality transparency. |
| Desk Score | 75/100C | 79/100C+ |
The verdict
Desk pick — NewSelfNewSelf takes this head-to-head with the higher Desk Score, 79/100 (C+) against 75/100 (C) for Jyra Health. Jyra Health still holds its ground where its strengths line up with yours.
Choose Jyra Health if…
Budget shoppers wanting very low-cost compounded semaglutide or tirzepatide in any state.
From $99/mo (lowest dose rung) sema · $133/mo (promo rate) tirz · All 50 states
Choose NewSelf if…
Lowest-cost compounded GLP-1 with pharmacy quality transparency.
$100/mo sema · $144/mo tirz · 49 states
FDAWarning letter issued to NewSelf Limited dba NewSelf in February 2026. See the FDA warning-letter database.
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: Jyra Health · NewSelf.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- CoreAge Rx vs Jyra Health
- CoreAge Rx vs NewSelf
- Jyra Health vs Sunlight
- NewSelf vs Sunlight
- Jyra Health vs Pepti
- NewSelf vs Pepti
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.