Head-to-head dispatch
He & She MD vs Tyde Wellness
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
He & She MD is a nationwide telehealth weight-loss clinic offering doctor-prescribed GLP-1 medications: compounded semaglutide and tirzepatide (injectable or oral) plus a microdose option, with brand-name…
Desk Score
Low entry pricing, oral options, and 50-state reach — a strong value pick for first-time GLP-1 patients.
Tyde Wellness takes this head-to-head with the higher Desk Score, 89/100 (B+) against 83/100 (B) for He & She MD. He & She MD still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
He & She MD
83/100
B
Tyde Wellness
89/100
B+
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | He & She MD | Tyde Wellness |
|---|---|---|
| Semaglutide | $139/mo (starting dose, promotional rate, compounded) | $149/mo |
| Tirzepatide | $199/mo (starting dose, compounded) | $249/mo |
| Coverage | All 50 states | All 50 states |
| Brand-name | Yes | Compounded only |
| Oral option | Yes | Yes |
| Best for | Readers who want transparent low intro-priced GLP-1 (injectable, oral, or microdose) with brand-name access. | First-timers who want an affordable, needle-optional on-ramp available anywhere in the country. |
| Desk Score | 83/100B | 89/100B+ |
The verdict
Desk pick — Tyde WellnessTyde Wellness takes this head-to-head with the higher Desk Score, 89/100 (B+) against 83/100 (B) for He & She MD. He & She MD still holds its ground where its strengths line up with yours.
Choose He & She MD if…
Readers who want transparent low intro-priced GLP-1 (injectable, oral, or microdose) with brand-name access.
$139/mo (starting dose, promotional rate, compounded) sema · $199/mo (starting dose, compounded) tirz · All 50 states
Choose Tyde Wellness if…
First-timers who want an affordable, needle-optional on-ramp available anywhere in the country.
$149/mo sema · $249/mo tirz · All 50 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: He & She MD · Tyde Wellness.
Also on the board
CoreAge Rx tops every dispatch at 94/100
Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.
More head-to-heads
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Or see the full comparison hub and the complete board.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.