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Head-to-head dispatch

He & She MD vs NuDay Rx

Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.

Dispatch #26Desk pick
He & She MD

He & She MD is a nationwide telehealth weight-loss clinic offering doctor-prescribed GLP-1 medications: compounded semaglutide and tirzepatide (injectable or oral) with brand-name Ozempic and Zepbound alongside, on a published 1/3/6/12-month plan table.

$249/mo month-to-month (the 1-month plan on its product-page table; 3-month $219/mo, 6-month $199/mo, 12-month $99/mo, each a single purchase of the term; the home page's 6-month block is $139/mo promo for the first 6 months, then renews at $1,194 per 6 months; compounded injectable) sema · $339/mo month-to-month (the 1-month plan on its product-page table; 3-month $309/mo, 6-month $289/mo, 12-month $159/mo, each a single purchase of the term; the home page's 6-month block is $199/mo promo for the first 6 months, then renews at $1,734 per 6 months; compounded injectable) tirz · Verified August 29, 2026

Marked down on: Its own FAQ says the pharmacy it names holds a license in 44 US states, none in California, Nevada, New Jersey, North Carolina, Texas, Massachusetts, Mississippi, New Hampshire, West Virginia or Delaware, and “cannot dispense sterile compounds” — while the same FAQ says GLP-1s ship everywhere except Louisiana. Injectable GLP-1s are sterile compounds, and the site never says which of its two pharmacies covers the gap

vs
Dispatch #132
NuDay Rx

NuDay Rx is a GLP-1 weight-loss telehealth service (on the CareValidate/careGLP platform) that pairs medication with video coaching and lifestyle support.

$249/mo (compounded) sema · $329/mo (compounded) tirz · Verified June 22, 2026

Marked down on: Compounded semaglutide ($249) is pricier than some budget competitors

He & She MD takes this head-to-head with the higher Desk Score, 83/100 (B) against 71/100 (C) for NuDay Rx. NuDay Rx still holds its ground where its strengths line up with yours.

Desk Score, dimension by dimension

Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.

He & She MD

83/100

B

Overall

NuDay Rx

71/100

C

Price transparency

78
86

State access

86
24

Molecule range

90
90

Onboarding speed

75
70

Support responsiveness

88
87

Licensing & trust

83
74

The spec sheet

FieldHe & She MDNuDay Rx
Semaglutide$249/mo month-to-month (the 1-month plan on its product-page table; 3-month $219/mo, 6-month $199/mo, 12-month $99/mo, each a single purchase of the term; the home page's 6-month block is $139/mo promo for the first 6 months, then renews at $1,194 per 6 months; compounded injectable)$249/mo (compounded)
Tirzepatide$339/mo month-to-month (the 1-month plan on its product-page table; 3-month $309/mo, 6-month $289/mo, 12-month $159/mo, each a single purchase of the term; the home page's 6-month block is $199/mo promo for the first 6 months, then renews at $1,734 per 6 months; compounded injectable)$329/mo (compounded)
CoverageAll states except Louisiana (GLP-1)Not listed on NuDay Rx's site (checked June 22, 2026)
Brand-nameYesYes
Oral optionYesYes
Best forPeople who want a published GLP-1 price ladder, injectable or oral, and are willing to prepay a term to reach the low rate.Shoppers wanting both compounded and brand GLP-1 options with coaching and a doctor consult.
Desk Score83/100B71/100C

The verdict

Desk pick — He & She MD

He & She MD takes this head-to-head with the higher Desk Score, 83/100 (B) against 71/100 (C) for NuDay Rx. NuDay Rx still holds its ground where its strengths line up with yours.

Choose He & She MD if…

People who want a published GLP-1 price ladder, injectable or oral, and are willing to prepay a term to reach the low rate.

$249/mo month-to-month (the 1-month plan on its product-page table; 3-month $219/mo, 6-month $199/mo, 12-month $99/mo, each a single purchase of the term; the home page's 6-month block is $139/mo promo for the first 6 months, then renews at $1,194 per 6 months; compounded injectable) sema · $339/mo month-to-month (the 1-month plan on its product-page table; 3-month $309/mo, 6-month $289/mo, 12-month $159/mo, each a single purchase of the term; the home page's 6-month block is $199/mo promo for the first 6 months, then renews at $1,734 per 6 months; compounded injectable) tirz · All states except Louisiana (GLP-1)

Choose NuDay Rx if…

Shoppers wanting both compounded and brand GLP-1 options with coaching and a doctor consult.

$249/mo (compounded) sema · $329/mo (compounded) tirz

Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: He & She MD · NuDay Rx.

Also here

CoreAge Rx tops every dispatch at 94/100

Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: one price at every dose, both molecules, all 50 states — but the $99 and $149 figures are 12-month plans paid up front, not a monthly bill.

More head-to-heads

Or see the full comparison hub and the complete ranking.

Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.