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Head-to-head dispatch

He & She MD vs HealthRX

Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.

Dispatch #25
He & She MD

He & She MD is a nationwide telehealth weight-loss clinic offering doctor-prescribed GLP-1 medications: compounded semaglutide and tirzepatide (injectable or oral), with brand-name…

Marked down on: Its own FAQ says the pharmacy it names holds a license in 44 US states, none in California, Nevada, New Jersey, North Carolina, Texas, Massachusetts, Mississippi, New Hampshire, West Virginia or Delaware, and “cannot dispense sterile compounds” — while the same FAQ says GLP-1s ship everywhere except Louisiana. Injectable GLP-1s are sterile compounds, and the site never says which of its two pharmacies covers the gap

vs
Dispatch #11Desk pick
HealthRX

A LegitScript-certified telehealth desk with a rare oral GLP tablet route alongside injectables and physician-reviewed intake.

Marked down on: Compounded medications are not FDA-approved

HealthRX takes this head-to-head with the higher Desk Score, 86/100 (B) against 83/100 (B) for He & She MD. He & She MD still holds its ground where its strengths line up with yours.

Desk Score, dimension by dimension

Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.

He & She MD

83/100

B

Overall

HealthRX

86/100

B

Price transparency

78
82

State access

86
80

Molecule range

90
94

Onboarding speed

75
84

Support responsiveness

88
82

Licensing & trust

83
90

The spec sheet

FieldHe & She MDHealthRX
Semaglutide$199/mo (month to month, compounded; every lower rate is a prepaid term)$190/mo month-to-month ($99 first month, renews at $165) · $99/mo on a 12-month prepay ($1,188)
Tirzepatide$299/mo (month to month, compounded; every lower rate is a prepaid term)$239/mo month-to-month ($149 first month, renews at $214) · $179/mo on a 12-month prepay ($2,148)
CoverageAll states except Louisiana (GLP-1)United States
Brand-nameYesYes
Oral optionYesYes
Best forReaders who want a published GLP-1 price ladder, injectable or oral, and are willing to prepay a term to reach the low rate.Patients who want a certified, physician-supervised program and the option of an oral tablet instead of an injection.
Desk Score83/100B86/100B

The verdict

Desk pick — HealthRX

HealthRX takes this head-to-head with the higher Desk Score, 86/100 (B) against 83/100 (B) for He & She MD. He & She MD still holds its ground where its strengths line up with yours.

Choose He & She MD if…

Readers who want a published GLP-1 price ladder, injectable or oral, and are willing to prepay a term to reach the low rate.

$199/mo (month to month, compounded; every lower rate is a prepaid term) sema · $299/mo (month to month, compounded; every lower rate is a prepaid term) tirz · All states except Louisiana (GLP-1)

Choose HealthRX if…

Patients who want a certified, physician-supervised program and the option of an oral tablet instead of an injection.

$190/mo month-to-month ($99 first month, renews at $165) · $99/mo on a 12-month prepay ($1,188) sema · $239/mo month-to-month ($149 first month, renews at $214) · $179/mo on a 12-month prepay ($2,148) tirz · United States

Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: He & She MD · HealthRX.

Also here

CoreAge Rx tops every dispatch at 94/100

Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.

More head-to-heads

Or see the full comparison hub and the complete ranking.

Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.