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Head-to-head dispatch

Harper Meds vs Rylo Health

Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.

Dispatch #187
Harper Meds

DTC telehealth weight-loss program (Nexus Health Solutions LLC) offering flat-rate compounded semaglutide and tirzepatide, with the consultation, prescription, medication, and shipping bundled into one…

Marked down on: Membership fee is non-refundable once paid

FDAWarning letter issued to Nexus Health Solutions LLC dba Harper Meds in June 2026. See the FDA warning-letter database.

vs
Dispatch #100Desk pick
Rylo Health

Texas-prescriber telehealth selling compounded semaglutide and tirzepatide alongside a peptide line, naming both its medical group and its dispensing pharmacy.

Marked down on: Headline $100 and $160 rates are limited to the first 20 patients; standard rates are $149 and $249

Rylo Health takes this head-to-head with the higher Desk Score, 76/100 (C) against 66/100 (C) for Harper Meds. Harper Meds still holds its ground where its strengths line up with yours.

Desk Score, dimension by dimension

Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.

Harper Meds

66/100

C

Overall

Rylo Health

76/100

C

Price transparency

94
68

State access

24
86

Molecule range

66
72

Onboarding speed

75
82

Support responsiveness

78
79

Licensing & trust

57
75

The spec sheet

FieldHarper MedsRylo Health
Semaglutide$149/mo$149/mo (promotional rate, compounded)
Tirzepatide$196/mo$249/mo (compounded)
CoverageCoverage not publishedAll 50 states
Brand-nameCompounded onlyCompounded only
Oral optionInjectable onlyInjectable only
Best forReaders who want flat-rate compounded GLP-1 with everything bundled into one price.Shoppers who want the pharmacy and medical group named before they buy.
Desk Score66/100C76/100C

The verdict

Desk pick — Rylo Health

Rylo Health takes this head-to-head with the higher Desk Score, 76/100 (C) against 66/100 (C) for Harper Meds. Harper Meds still holds its ground where its strengths line up with yours.

Choose Harper Meds if…

Readers who want flat-rate compounded GLP-1 with everything bundled into one price.

$149/mo sema · $196/mo tirz · Coverage not published

FDAWarning letter issued to Nexus Health Solutions LLC dba Harper Meds in June 2026. See the FDA warning-letter database.

Choose Rylo Health if…

Shoppers who want the pharmacy and medical group named before they buy.

$149/mo (promotional rate, compounded) sema · $249/mo (compounded) tirz · All 50 states

Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Harper Meds · Rylo Health.

Also here

CoreAge Rx tops every dispatch at 94/100

Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.

More head-to-heads

Or see the full comparison hub and the complete ranking.

Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.