Head-to-head dispatch
CLYR Health vs He & She MD
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
CLYR Health is a Florida-based telehealth pharmacy offering compounded GLP-1 weight-loss injections alongside sexual-health, longevity and wellness treatments.
Marked down on: State availability gated behind intake; not published on the marketing site
Desk Score
He & She MD is a nationwide telehealth weight-loss clinic offering doctor-prescribed GLP-1 medications: compounded semaglutide and tirzepatide (injectable or oral), with brand-name…
Marked down on: Its own FAQ says the pharmacy it names holds a license in 44 US states, none in California, Nevada, New Jersey, North Carolina, Texas, Massachusetts, Mississippi, New Hampshire, West Virginia or Delaware, and “cannot dispense sterile compounds” — while the same FAQ says GLP-1s ship everywhere except Louisiana. Injectable GLP-1s are sterile compounds, and the site never says which of its two pharmacies covers the gap
He & She MD takes this head-to-head with the higher Desk Score, 83/100 (B) against 68/100 (C) for CLYR Health. CLYR Health still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
CLYR Health
68/100
C
He & She MD
83/100
B
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | CLYR Health | He & She MD |
|---|---|---|
| Semaglutide | $229/mo (compounded) | $199/mo (month to month, compounded; every lower rate is a prepaid term) |
| Tirzepatide | $249/mo (compounded) | $299/mo (month to month, compounded; every lower rate is a prepaid term) |
| Coverage | Coverage not published | All states except Louisiana (GLP-1) |
| Brand-name | Yes | Yes |
| Oral option | Yes | Yes |
| Best for | Readers who want flat-rate compounded GLP-1 with pricing that does not increase as your dose goes up. | Readers who want a published GLP-1 price ladder, injectable or oral, and are willing to prepay a term to reach the low rate. |
| Desk Score | 68/100C | 83/100B |
The verdict
Desk pick — He & She MDHe & She MD takes this head-to-head with the higher Desk Score, 83/100 (B) against 68/100 (C) for CLYR Health. CLYR Health still holds its ground where its strengths line up with yours.
Choose CLYR Health if…
Readers who want flat-rate compounded GLP-1 with pricing that does not increase as your dose goes up.
$229/mo (compounded) sema · $249/mo (compounded) tirz · Coverage not published
Choose He & She MD if…
Readers who want a published GLP-1 price ladder, injectable or oral, and are willing to prepay a term to reach the low rate.
$199/mo (month to month, compounded; every lower rate is a prepaid term) sema · $299/mo (month to month, compounded; every lower rate is a prepaid term) tirz · All states except Louisiana (GLP-1)
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: CLYR Health · He & She MD.
Also here
CoreAge Rx tops every dispatch at 94/100
Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.
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Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.