Head-to-head dispatch
Center for Medical Weight Loss (CMWL) vs Rylo Health
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
Center for Medical Weight Loss (CMWL) runs a 100 percent online, physician-supervised GLP-1 program using compounded semaglutide and tirzepatide with flat any-dose pricing.
Marked down on: Some states are ineligible and the eligible-state list is not published
Desk Score
Texas-prescriber telehealth selling compounded semaglutide and tirzepatide alongside a peptide line, naming both its medical group and its dispensing pharmacy.
Marked down on: Headline $100 and $160 rates are limited to the first 20 patients; standard rates are $149 and $249
Rylo Health takes this head-to-head with the higher Desk Score, 76/100 (C) against 64/100 (C) for Center for Medical Weight Loss (CMWL). Center for Medical Weight Loss (CMWL) still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Center for Medical Weight Loss (CMWL)
64/100
C
Rylo Health
76/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Center for Medical Weight Loss (CMWL) | Rylo Health |
|---|---|---|
| Semaglutide | $149/mo (all doses, compounded) | $149/mo (promotional rate, compounded) |
| Tirzepatide | $239/mo (all doses, compounded) | $249/mo (compounded) |
| Coverage | Coverage not published | All 50 states |
| Brand-name | Compounded only | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | Readers who want budget-conscious patients wanting flat any-dose compounded glp-1 from an established program. | Shoppers who want the pharmacy and medical group named before they buy. |
| Desk Score | 64/100C | 76/100C |
The verdict
Desk pick — Rylo HealthRylo Health takes this head-to-head with the higher Desk Score, 76/100 (C) against 64/100 (C) for Center for Medical Weight Loss (CMWL). Center for Medical Weight Loss (CMWL) still holds its ground where its strengths line up with yours.
Choose Center for Medical Weight Loss (CMWL) if…
Readers who want budget-conscious patients wanting flat any-dose compounded glp-1 from an established program.
$149/mo (all doses, compounded) sema · $239/mo (all doses, compounded) tirz · Coverage not published
Choose Rylo Health if…
Shoppers who want the pharmacy and medical group named before they buy.
$149/mo (promotional rate, compounded) sema · $249/mo (compounded) tirz · All 50 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Center for Medical Weight Loss (CMWL) · Rylo Health.
Also here
CoreAge Rx tops every dispatch at 94/100
Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.
More head-to-heads
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Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.