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Head-to-head dispatch

10rx vs NewSelf

Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.

Dispatch #308
10rx

10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin…

Marked down on: Doesn't publish its legal operating entity, so accountability is hard to verify

vs
Dispatch #60Desk pick
NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo).

Marked down on: Not available in Mississippi and Louisiana

FDAWarning letter issued to NewSelf Limited dba NewSelf in February 2026. See the FDA warning-letter database.

NewSelf takes this head-to-head with the higher Desk Score, 79/100 (C+) against 60/100 (C) for 10rx. 10rx still holds its ground where its strengths line up with yours.

Desk Score, dimension by dimension

Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.

10rx

60/100

C

Overall

NewSelf

79/100

C+

Price transparency

78
86

State access

24
78

Molecule range

66
66

Onboarding speed

74
84

Support responsiveness

66
84

Licensing & trust

45
71

The spec sheet

Field10rxNewSelf
Semaglutide$100/mo (compounded)$100/mo (compounded)
Tirzepatide$150/mo (compounded)$144/mo (compounded)
CoverageCoverage not published49 states
Brand-nameCompounded onlyCompounded only
Oral optionInjectable onlyInjectable only
Best forReaders who want budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons.Readers who want lowest-cost compounded GLP-1 with pharmacy quality transparency.
Desk Score60/100C79/100C+

The verdict

Desk pick — NewSelf

NewSelf takes this head-to-head with the higher Desk Score, 79/100 (C+) against 60/100 (C) for 10rx. 10rx still holds its ground where its strengths line up with yours.

Choose 10rx if…

Readers who want budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons.

$100/mo (compounded) sema · $150/mo (compounded) tirz · Coverage not published

Choose NewSelf if…

Readers who want lowest-cost compounded GLP-1 with pharmacy quality transparency.

$100/mo (compounded) sema · $144/mo (compounded) tirz · 49 states

FDAWarning letter issued to NewSelf Limited dba NewSelf in February 2026. See the FDA warning-letter database.

Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: 10rx · NewSelf.

Also here

CoreAge Rx tops every dispatch at 94/100

Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.

More head-to-heads

Or see the full comparison hub and the complete ranking.

Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.