Head-to-head comparison
Vaylen vs ZYP Medical
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
The strongest all-rounder among the newer entrants — low pricing, brand access, oral routes, and all 50 states on one account.
$179/mo sema · $239/mo tirz
Marked down on: Newer operator with a shorter track record
Desk Score
ZYP Medical is a men's-health-oriented telehealth practice prescribing compounded GLP-1 medications for weight loss across six states.
$150/mo sema · $233/mo tirz · Verified July 2026
Marked down on: Compounded medications are not FDA-approved
Vaylen takes this head-to-head with the higher Desk Score, 90/100 (A−) against 71/100 (C) for ZYP Medical. ZYP Medical still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Vaylen
90/100
A−
ZYP Medical
71/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Vaylen | ZYP Medical |
|---|---|---|
| Semaglutide | $179/mo$179/mo | $150/mo$150/mo |
| Tirzepatide | $239/mo$239/mo | $233/mo$233/mo |
| Coverage | All 50 states | 6 states |
| Brand-name | Yes | Compounded only |
| Oral option | Yes | Yes |
| Best for | People who want maximum optionality — brand or compounded, oral or injectable — without giving up nationwide reach. | Men in NE, IA, SD, KS, CO, or AZ wanting low-cost compounded GLP-1s with oral option. |
| Desk Score | 90/100A− | 71/100C |
The verdict
Desk pick — VaylenVaylen takes this head-to-head with the higher Desk Score, 90/100 (A−) against 71/100 (C) for ZYP Medical. ZYP Medical still holds its ground where its strengths line up with yours.
Choose Vaylen if…
People who want maximum optionality — brand or compounded, oral or injectable — without giving up nationwide reach.
$179/mo sema · $239/mo tirz · All 50 states
Choose ZYP Medical if…
Men in NE, IA, SD, KS, CO, or AZ wanting low-cost compounded GLP-1s with oral option.
$150/mo sema · $233/mo tirz · 6 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: Vaylen · ZYP Medical.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
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Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.