Head-to-head comparison
tru Weight Loss vs Tryozi
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
tru Weight Loss (truhealthnow) is a physician-directed telehealth program prescribing compounded semaglutide and tirzepatide, shipped from US-licensed compounding pharmacies.
$299/mo (3-month prepay) sema · $399/mo (3-month prepay) tirz · Verified July 2026
Marked down on: Requires a 3-month commitment before you can cancel
Desk Score
Florida telehealth selling compounded GLP-1 injections at a flat price that does not rise with dose, naming all four of its 503A compounding pharmacies.
$279/mo sema · $379/mo tirz · Verified July 2026
Marked down on: Headline $139 is a first-month half-price offer; the ongoing rate is $279
Tryozi takes this head-to-head with the higher Desk Score, 81/100 (B−) against 63/100 (C) for tru Weight Loss. tru Weight Loss still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
tru Weight Loss
63/100
C
Tryozi
81/100
B−
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | tru Weight Loss | Tryozi |
|---|---|---|
| Semaglutide | $299/mo3-month prepay$299/mo (all doses, 3-month plan, compounded) | $279/mo$279/mo (compounded) |
| Tirzepatide | $399/mo3-month prepay$399/mo (all doses, 3-month plan, compounded) | $379/mo$379/mo (compounded) |
| Coverage | Not listed on tru Weight Loss's site (checked July 2026) | All 50 states |
| Brand-name | Compounded only | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | Patients wanting all-inclusive md-directed glp-1 care with labs and coaching. | Shoppers who want the pharmacy named and a price that does not climb with dose. |
| Desk Score | 63/100C | 81/100B− |
The verdict
Desk pick — TryoziTryozi takes this head-to-head with the higher Desk Score, 81/100 (B−) against 63/100 (C) for tru Weight Loss. tru Weight Loss still holds its ground where its strengths line up with yours.
Choose tru Weight Loss if…
Patients wanting all-inclusive md-directed glp-1 care with labs and coaching.
$299/mo (3-month prepay) sema · $399/mo (3-month prepay) tirz
Choose Tryozi if…
Shoppers who want the pharmacy named and a price that does not climb with dose.
$279/mo sema · $379/mo tirz · All 50 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: tru Weight Loss · Tryozi.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- CoreAge Rx vs tru Weight Loss
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- The Edit vs Tryozi
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.