Head-to-head comparison
Trellis Vitality vs Youth & Soul
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
Trellis Vitality prices both molecules flat at every dose before intake and names its pharmacy and prescriber, while its own GLP-1 FAQ contradicts the all-50-states banner above it.
From $150/mo sema · From $199/mo tirz · Verified September 2026
Marked down on: The banner says all 50 states while the GLP-1 program's own FAQ says it is not offered in every state, naming Connecticut, Ohio and South Carolina.
Desk Score
Ten-vertical telehealth marketplace selling compounded GLP-1 tiers alongside HRT, ED, nootropics and peptides, running on the Bask Health platform.
From $149/mo (lowest dose rung) sema · $399/mo tirz · Verified July 2026
Marked down on: Describes its compounded medications as FDA-Approved Compounds, which is false: compounded drugs are not FDA-approved
Trellis Vitality takes this head-to-head with the higher Desk Score, 81/100 (B−) against 55/100 (C) for Youth & Soul. Youth & Soul still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Trellis Vitality
81/100
B−
Youth & Soul
55/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Trellis Vitality | Youth & Soul |
|---|---|---|
| Semaglutide | From $150/moFrom $150/mo (all doses, compounded) | From $149/molowest dose rung$149/mo (starting dose, compounded) |
| Tirzepatide | From $199/moFrom $199/mo (all doses, compounded) | $399/mo$399/mo (compounded) |
| Coverage | All 50 states claimed; GLP-1 not offered in every state | Not listed on Youth & Soul's site (checked July 2026) |
| Brand-name | Compounded only | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | Anyone who wants a flat dose price and will check whether their state is one the GLP-1 program actually covers. | Shoppers who want many treatment categories in one account and are willing to verify claims themselves. |
| Desk Score | 81/100B− | 55/100C |
The verdict
Desk pick — Trellis VitalityTrellis Vitality takes this head-to-head with the higher Desk Score, 81/100 (B−) against 55/100 (C) for Youth & Soul. Youth & Soul still holds its ground where its strengths line up with yours.
Choose Trellis Vitality if…
Anyone who wants a flat dose price and will check whether their state is one the GLP-1 program actually covers.
From $150/mo sema · From $199/mo tirz · All 50 states claimed; GLP-1 not offered in every state
Choose Youth & Soul if…
Shoppers who want many treatment categories in one account and are willing to verify claims themselves.
From $149/mo (lowest dose rung) sema · $399/mo tirz
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: Trellis Vitality · Youth & Soul.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
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- Ondra Health vs Youth & Soul
- Trellis Vitality vs Tyde Wellness
- Tyde Wellness vs Youth & Soul
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.