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Head-to-head dispatch

Silhouette MD vs Zera Health

Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.

Dispatch #385
Silhouette MD

Concierge-style GLP-1 telehealth offering compounded semaglutide and tirzepatide in both injectable and oral forms, with provider oversight and full-service support included on every plan.

Marked down on: Tirzepatide ($299/mo) and oral options ($263–$325/mo) priced above many compounded competitors

vs
Dispatch #41Desk pick
Zera Health

Zera Health is a telehealth platform for compounded GLP-1 weight loss — semaglutide from $149/mo, tirzepatide from $199/mo, plus oral and low-dose microdose options — prescribed by licensed physicians in…

Marked down on: Operates as a technology platform, not the medical provider itself

Zera Health takes this head-to-head with the higher Desk Score, 82/100 (B−) against 54/100 (C) for Silhouette MD. Silhouette MD still holds its ground where its strengths line up with yours.

Desk Score, dimension by dimension

Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.

Silhouette MD

54/100

C

Overall

Zera Health

82/100

B−

Price transparency

30
86

State access

24
86

Molecule range

77
77

Onboarding speed

72
78

Support responsiveness

79
80

Licensing & trust

73
83

The spec sheet

FieldSilhouette MDZera Health
Semaglutide$149/mo (compounded)$149/mo (compounded)
Tirzepatide$299/mo (compounded)$199/mo (compounded)
CoverageCoverage not publishedAll 50 states
Brand-nameCompounded onlyCompounded only
Oral optionYesYes
Best forPeople who want hands-on concierge support alongside compounded GLP-1 treatment.Readers who want budget GLP-1 shoppers who want flat all-dose pricing and a named 503A pharmacy.
Desk Score54/100C82/100B−

The verdict

Desk pick — Zera Health

Zera Health takes this head-to-head with the higher Desk Score, 82/100 (B−) against 54/100 (C) for Silhouette MD. Silhouette MD still holds its ground where its strengths line up with yours.

Choose Silhouette MD if…

People who want hands-on concierge support alongside compounded GLP-1 treatment.

$149/mo (compounded) sema · $299/mo (compounded) tirz · Coverage not published

Choose Zera Health if…

Readers who want budget GLP-1 shoppers who want flat all-dose pricing and a named 503A pharmacy.

$149/mo (compounded) sema · $199/mo (compounded) tirz · All 50 states

Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Silhouette MD · Zera Health.

Also here

CoreAge Rx tops every dispatch at 94/100

Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.

More head-to-heads

Or see the full comparison hub and the complete ranking.

Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.