Head-to-head dispatch
Sesame Care vs Trillium Meds
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
An established national telehealth marketplace with the widest real brand-name GLP-1 access on the board — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency.
Desk Score
Trillium Meds is a small, owner-operated telehealth platform based in Portland, OR that connects patients with independent licensed providers and FDA-registered compounding pharmacies for compounded…
Sesame Care takes this head-to-head with the higher Desk Score, 87/100 (B+) against 77/100 (C+) for Trillium Meds. Trillium Meds still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Sesame Care
87/100
B+
Trillium Meds
77/100
C+
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Sesame Care | Trillium Meds |
|---|---|---|
| Semaglutide | From $149/mo (brand Wegovy pill) | $119/mo (3-month plan, compounded) |
| Tirzepatide | Brand Zepbound (price varies) | $199/mo (3-month plan, compounded) |
| Coverage | Nationwide marketplace | All 50 states |
| Brand-name | Yes | Compounded only |
| Oral option | Yes | Injectable only |
| Best for | Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program. | Readers who want legitScript-certified compounded GLP-1 telehealth, all 50 states + PR; sema $119/mo, tirz $199/mo (3-mo). |
| Desk Score | 87/100B+ | 77/100C+ |
The verdict
Desk pick — Sesame CareSesame Care takes this head-to-head with the higher Desk Score, 87/100 (B+) against 77/100 (C+) for Trillium Meds. Trillium Meds still holds its ground where its strengths line up with yours.
Choose Sesame Care if…
Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.
From $149/mo (brand Wegovy pill) sema · Brand Zepbound (price varies) tirz · Nationwide marketplace
Choose Trillium Meds if…
Readers who want legitScript-certified compounded GLP-1 telehealth, all 50 states + PR; sema $119/mo, tirz $199/mo (3-mo).
$119/mo (3-month plan, compounded) sema · $199/mo (3-month plan, compounded) tirz · All 50 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Sesame Care · Trillium Meds.
Also on the board
CoreAge Rx tops every dispatch at 94/100
Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.
More head-to-heads
- Sesame Care vs CoreAge Rx
- Trillium Meds vs Vaylen
- Sesame Care vs Strut Health
- Trillium Meds vs Ondra Health
- Sesame Care vs Invigor Medical
- Trillium Meds vs Vytora Health
Or see the full comparison hub and the complete board.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.