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Head-to-head dispatch

Rex MD vs Sesame Care

Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.

Dispatch #134
Rex MD

Rex MD is a US-based men's-health telehealth platform (a LifeMD brand) offering a 100 percent online GLP-1 weight-management program.

vs
Dispatch #7Desk pick
Sesame Care

An established national telehealth marketplace with the widest real brand-name GLP-1 access on the board — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency.

Sesame Care takes this head-to-head with the higher Desk Score, 87/100 (B+) against 70/100 (C) for Rex MD. Rex MD still holds its ground where its strengths line up with yours.

Desk Score, dimension by dimension

Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.

Rex MD

70/100

C

Overall

Sesame Care

87/100

B+

Price transparency

38
84

State access

86
92

Molecule range

79
94

Onboarding speed

72
84

Support responsiveness

79
80

Licensing & trust

84
92

The spec sheet

FieldRex MDSesame Care
Semaglutide$199/mo (brand-name)From $149/mo (brand Wegovy pill)
Tirzepatide$349/mo (brand Zepbound)Brand Zepbound (price varies)
CoverageAll 50 statesNationwide marketplace
Brand-nameYesYes
Oral optionInjectable onlyYes
Best forReaders who want men wanting a flat-fee, all-inclusive branded GLP-1 program nationwide.Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.
Desk Score70/100C87/100B+

The verdict

Desk pick — Sesame Care

Sesame Care takes this head-to-head with the higher Desk Score, 87/100 (B+) against 70/100 (C) for Rex MD. Rex MD still holds its ground where its strengths line up with yours.

Choose Rex MD if…

Readers who want men wanting a flat-fee, all-inclusive branded GLP-1 program nationwide.

$199/mo (brand-name) sema · $349/mo (brand Zepbound) tirz · All 50 states

Choose Sesame Care if…

Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.

From $149/mo (brand Wegovy pill) sema · Brand Zepbound (price varies) tirz · Nationwide marketplace

Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Rex MD · Sesame Care.

Also on the board

CoreAge Rx tops every dispatch at 94/100

Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.

More head-to-heads

Or see the full comparison hub and the complete board.

Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.