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Head-to-head dispatch

PlushCare vs Tuyo Health

Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.

Dispatch #117Desk pick
PlushCare

Established virtual primary-care telehealth platform (subsidiary of Transcarent, Inc., a Delaware corporation, alongside Accolade, 2nd.MD, and 98point6 by Transcarent).

Marked down on: Facing a California class action alleging deceptive subscription enrollment and unauthorized charges after cancellation

vs
Dispatch #257
Tuyo Health

Tuyo Health (tuyohealth.com) is a US telehealth weight-loss program founded by Dr.

Marked down on: Service-area states not published

FDAWarning letter issued to Tuyo Health, Inc. dba Tuyo Health in September 2025. See the FDA warning-letter database.

PlushCare takes this head-to-head with the higher Desk Score, 73/100 (C) against 63/100 (C) for Tuyo Health. Tuyo Health still holds its ground where its strengths line up with yours.

Desk Score, dimension by dimension

Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.

PlushCare

73/100

C

Overall

Tuyo Health

63/100

C

Price transparency

78
94

State access

86
24

Molecule range

79
79

Onboarding speed

49
47

Support responsiveness

75
73

Licensing & trust

58
43

The spec sheet

FieldPlushCareTuyo Health
Semaglutide$149/mo (starting dose, compounded)$155/mo
Tirzepatide$399/mo (starting dose, compounded)$279/mo
CoverageAll 50 statesCoverage not published
Brand-nameYesYes
Oral optionInjectable onlyInjectable only
Best forReaders who want virtual primary care that can also prescribe GLP-1s.Shoppers wanting low-cost compounded glp-1 on an all-inclusive plan.
Desk Score73/100C63/100C

The verdict

Desk pick — PlushCare

PlushCare takes this head-to-head with the higher Desk Score, 73/100 (C) against 63/100 (C) for Tuyo Health. Tuyo Health still holds its ground where its strengths line up with yours.

Choose PlushCare if…

Readers who want virtual primary care that can also prescribe GLP-1s.

$149/mo (starting dose, compounded) sema · $399/mo (starting dose, compounded) tirz · All 50 states

Choose Tuyo Health if…

Shoppers wanting low-cost compounded glp-1 on an all-inclusive plan.

$155/mo sema · $279/mo tirz · Coverage not published

FDAWarning letter issued to Tuyo Health, Inc. dba Tuyo Health in September 2025. See the FDA warning-letter database.

Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: PlushCare · Tuyo Health.

Also here

CoreAge Rx tops every dispatch at 94/100

Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.

More head-to-heads

Or see the full comparison hub and the complete ranking.

Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.