Head-to-head comparison
PlushCare vs Tuyo Health
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
Established virtual primary-care telehealth platform (subsidiary of Transcarent, Inc., a Delaware corporation, alongside Accolade, 2nd.MD, and 98point6 by Transcarent).
From $149/mo (lowest dose rung) sema · From $399/mo (lowest dose rung) tirz · Verified July 2026
Marked down on: Facing a California class action alleging deceptive subscription enrollment and unauthorized charges after cancellation
Desk Score
Tuyo Health (tuyohealth.com) is a US telehealth weight-loss program founded by Dr.
$155/mo sema · $279/mo tirz · Verified July 2026
Marked down on: Service-area states not published
FDAWarning letter issued to Tuyo Health, Inc. dba Tuyo Health in September 2025. See the FDA warning-letter database.
PlushCare takes this head-to-head with the higher Desk Score, 73/100 (C) against 63/100 (C) for Tuyo Health. Tuyo Health still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
PlushCare
73/100
C
Tuyo Health
63/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | PlushCare | Tuyo Health |
|---|---|---|
| Semaglutide | From $149/molowest dose rung$149/mo (starting dose, compounded) | $155/mo$155/mo |
| Tirzepatide | From $399/molowest dose rung$399/mo (starting dose, compounded) | $279/mo$279/mo |
| Coverage | All 50 states | Not listed on Tuyo Health's site (checked July 2026) |
| Brand-name | Yes | Yes |
| Oral option | Injectable only | Injectable only |
| Best for | Virtual primary care that can also prescribe GLP-1s. | Shoppers wanting low-cost compounded glp-1 on an all-inclusive plan. |
| Desk Score | 73/100C | 63/100C |
The verdict
Desk pick — PlushCarePlushCare takes this head-to-head with the higher Desk Score, 73/100 (C) against 63/100 (C) for Tuyo Health. Tuyo Health still holds its ground where its strengths line up with yours.
Choose PlushCare if…
Virtual primary care that can also prescribe GLP-1s.
From $149/mo (lowest dose rung) sema · From $399/mo (lowest dose rung) tirz · All 50 states
Choose Tuyo Health if…
Shoppers wanting low-cost compounded glp-1 on an all-inclusive plan.
$155/mo sema · $279/mo tirz
FDAWarning letter issued to Tuyo Health, Inc. dba Tuyo Health in September 2025. See the FDA warning-letter database.
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: PlushCare · Tuyo Health.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- CoreAge Rx vs PlushCare
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- Effecty vs Tuyo Health
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.