Head-to-head dispatch
PlexusDx vs Vaylen
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
PlexusDx (plexusdx.com) is a US GLP-1 telehealth platform offering compounded weight-loss medications with licensed providers in all 50 states.
Desk Score
The strongest all-rounder among the newer entrants — low pricing, brand access, oral routes, and all 50 states on one account.
Vaylen takes this head-to-head with the higher Desk Score, 91/100 (A−) against 75/100 (C) for PlexusDx. PlexusDx still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
PlexusDx
75/100
C
Vaylen
91/100
A−
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | PlexusDx | Vaylen |
|---|---|---|
| Semaglutide | $149/mo (starting dose, compounded) | $179/mo |
| Tirzepatide | $249/mo (starting dose, compounded) | $239/mo |
| Coverage | All 50 states | All 50 states |
| Brand-name | Compounded only | Yes |
| Oral option | Injectable only | Yes |
| Best for | Shoppers wanting nationwide compounded GLP-1 with optional genetic-test personalization. | People who want maximum optionality — brand or compounded, oral or injectable — without giving up nationwide reach. |
| Desk Score | 75/100C | 91/100A− |
The verdict
Desk pick — VaylenVaylen takes this head-to-head with the higher Desk Score, 91/100 (A−) against 75/100 (C) for PlexusDx. PlexusDx still holds its ground where its strengths line up with yours.
Choose PlexusDx if…
Shoppers wanting nationwide compounded GLP-1 with optional genetic-test personalization.
$149/mo (starting dose, compounded) sema · $249/mo (starting dose, compounded) tirz · All 50 states
Choose Vaylen if…
People who want maximum optionality — brand or compounded, oral or injectable — without giving up nationwide reach.
$179/mo sema · $239/mo tirz · All 50 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: PlexusDx · Vaylen.
Also on the board
CoreAge Rx tops every dispatch at 94/100
Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.
More head-to-heads
- PlexusDx vs CoreAge Rx
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- Vaylen vs Invigor Medical
- PlexusDx vs Vytora Health
- Vaylen vs Sesame Care
Or see the full comparison hub and the complete board.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.