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Head-to-head comparison

Optimized Health vs TelePeptide

Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.

Ranked #70Desk pick
Optimized Health

Verified and oral-capable, but availability is limited to five states — a narrow-reach specialist.

$200/mo sema · $250/mo tirz

Marked down on: Only five states served

vs
Ranked #221
TelePeptide

TelePeptide is a LegitScript-certified US direct-pay telehealth practice offering physician-supervised compounded GLP-1 therapy.

$199/mo (12-month prepay) sema · $219/mo (12-month prepay) tirz · Verified July 2026

Marked down on: Compounded medications are not FDA-approved; no pharmacy partner named publicly

Optimized Health takes this head-to-head with the higher Desk Score, 79/100 (C+) against 67/100 (C) for TelePeptide. TelePeptide still holds its ground where its strengths line up with yours.

Desk Score, dimension by dimension

Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.

Optimized Health

79/100

C+

Overall

TelePeptide

67/100

C

Price transparency

82
68

State access

55
24

Molecule range

90
83

Onboarding speed

82
80

Support responsiveness

82
85

Licensing & trust

88
84

The spec sheet

FieldOptimized HealthTelePeptide
Semaglutide$200/mo$200/mo$199/mo12-month prepay$199/mo (starting dose, annual plan, compounded oral)
Tirzepatide$250/mo$250/mo$219/mo12-month prepay$219/mo (starting dose, annual plan, compounded oral)
CoverageMO, IA, KS, UT, WANot listed on TelePeptide's site (checked July 2026)
Brand-nameCompounded onlyCompounded only
Oral optionYesYes
Best forPatients in MO, IA, KS, UT, or WA who want a verified, oral-capable program.All-in compounded GLP-1 (sema/tirz, injectable + oral) from $169/mo; LegitScript-certified, 48 states.
Desk Score79/100C+67/100C

The verdict

Desk pick — Optimized Health

Optimized Health takes this head-to-head with the higher Desk Score, 79/100 (C+) against 67/100 (C) for TelePeptide. TelePeptide still holds its ground where its strengths line up with yours.

Choose Optimized Health if…

Patients in MO, IA, KS, UT, or WA who want a verified, oral-capable program.

$200/mo sema · $250/mo tirz · MO, IA, KS, UT, WA

Choose TelePeptide if…

All-in compounded GLP-1 (sema/tirz, injectable + oral) from $169/mo; LegitScript-certified, 48 states.

$199/mo (12-month prepay) sema · $219/mo (12-month prepay) tirz

Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: Optimized Health · TelePeptide.

Also here

CoreAge Rx leads the whole ranking at 94/100

Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.

More head-to-heads

Or see the full comparison hub and the complete ranking.

Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.