Skip to content
GLP-1 Desk
Menu

Head-to-head dispatch

Optimized Health vs Sesame Care

Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.

Dispatch #37
Optimized Health

Verified and oral-capable, but availability is limited to five states — a narrow-reach specialist.

vs
Dispatch #7Desk pick
Sesame Care

An established national telehealth marketplace with the widest real brand-name GLP-1 access on the board — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency.

Sesame Care takes this head-to-head with the higher Desk Score, 87/100 (B+) against 78/100 (C+) for Optimized Health. Optimized Health still holds its ground where its strengths line up with yours.

Desk Score, dimension by dimension

Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.

Optimized Health

78/100

C+

Overall

Sesame Care

87/100

B+

Price transparency

82
84

State access

55
92

Molecule range

90
94

Onboarding speed

82
84

Support responsiveness

82
80

Licensing & trust

88
92

The spec sheet

FieldOptimized HealthSesame Care
Semaglutide$200/moFrom $149/mo (brand Wegovy pill)
Tirzepatide$250/moBrand Zepbound (price varies)
CoverageMO, IA, KS, UT, WANationwide marketplace
Brand-nameCompounded onlyYes
Oral optionYesYes
Best forPatients in MO, IA, KS, UT, or WA who want a verified, oral-capable program.Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.
Desk Score78/100C+87/100B+

The verdict

Desk pick — Sesame Care

Sesame Care takes this head-to-head with the higher Desk Score, 87/100 (B+) against 78/100 (C+) for Optimized Health. Optimized Health still holds its ground where its strengths line up with yours.

Choose Optimized Health if…

Patients in MO, IA, KS, UT, or WA who want a verified, oral-capable program.

$200/mo sema · $250/mo tirz · MO, IA, KS, UT, WA

Choose Sesame Care if…

Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.

From $149/mo (brand Wegovy pill) sema · Brand Zepbound (price varies) tirz · Nationwide marketplace

Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Optimized Health · Sesame Care.

Also on the board

CoreAge Rx tops every dispatch at 94/100

Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.

More head-to-heads

Or see the full comparison hub and the complete board.

Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.