Head-to-head comparison
Nucore Health vs Tryozi
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
Nucore Health is a physician-owned, LegitScript-certified telehealth platform serving all 50 states, focused on GLP-1 and longevity care.
From $299/mo (lowest dose rung) sema · From $199/mo (lowest dose rung) tirz · Verified June 2026
Marked down on: Published pricing is gated behind the intake quiz — no upfront cost shown
Desk Score
Florida telehealth selling compounded GLP-1 injections at a flat price that does not rise with dose, naming all four of its 503A compounding pharmacies.
$279/mo sema · $379/mo tirz · Verified July 2026
Marked down on: Headline $139 is a first-month half-price offer; the ongoing rate is $279
Tryozi takes this head-to-head with the higher Desk Score, 81/100 (B−) against 65/100 (C) for Nucore Health. Nucore Health still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Nucore Health
65/100
C
Tryozi
81/100
B−
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Nucore Health | Tryozi |
|---|---|---|
| Semaglutide | From $299/molowest dose rung$299/mo (starting dose, compounded) | $279/mo$279/mo (compounded) |
| Tirzepatide | From $199/molowest dose rung$199/mo (microdose tier, compounded) | $379/mo$379/mo (compounded) |
| Coverage | Not listed on Nucore Health's site (checked June 2026) | All 50 states |
| Brand-name | Compounded only | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | Longevity-minded patients wanting microdose GLP-1, NAD+ and sermorelin from a LegitScript-certified clinic. | Shoppers who want the pharmacy named and a price that does not climb with dose. |
| Desk Score | 65/100C | 81/100B− |
The verdict
Desk pick — TryoziTryozi takes this head-to-head with the higher Desk Score, 81/100 (B−) against 65/100 (C) for Nucore Health. Nucore Health still holds its ground where its strengths line up with yours.
Choose Nucore Health if…
Longevity-minded patients wanting microdose GLP-1, NAD+ and sermorelin from a LegitScript-certified clinic.
From $299/mo (lowest dose rung) sema · From $199/mo (lowest dose rung) tirz
Choose Tryozi if…
Shoppers who want the pharmacy named and a price that does not climb with dose.
$279/mo sema · $379/mo tirz · All 50 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: Nucore Health · Tryozi.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- CoreAge Rx vs Nucore Health
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- The Edit vs Tryozi
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.