Head-to-head comparison
NP2GO vs Trellis Vitality
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
NP2GO is a nurse-practitioner-led hybrid telehealth and clinic operation based in Edmond, Oklahoma, founded in 2019 and affiliated with the Obesity Medicine Association.
From $150/mo (lowest dose rung) sema · From $250/mo (lowest dose rung) tirz · Verified July 2026
Marked down on: High-dose tirzepatide runs $475–$600/mo on Pay As You Go (membership at $399/mo is better for high doses)
Desk Score
Trellis Vitality prices both molecules flat at every dose before intake and names its pharmacy and prescriber, while its own GLP-1 FAQ contradicts the all-50-states banner above it.
From $150/mo sema · From $199/mo tirz · Verified September 2026
Marked down on: The banner says all 50 states while the GLP-1 program's own FAQ says it is not offered in every state, naming Connecticut, Ohio and South Carolina.
Trellis Vitality takes this head-to-head with the higher Desk Score, 81/100 (B−) against 63/100 (C) for NP2GO. NP2GO still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
NP2GO
63/100
C
Trellis Vitality
81/100
B−
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | NP2GO | Trellis Vitality |
|---|---|---|
| Semaglutide | From $150/molowest dose rung$150/mo (0.25 mg dose, compounded) | From $150/moFrom $150/mo (all doses, compounded) |
| Tirzepatide | From $250/molowest dose rung$250/mo (2.5 mg dose, compounded) | From $199/moFrom $199/mo (all doses, compounded) |
| Coverage | 40 states | All 50 states claimed; GLP-1 not offered in every state |
| Brand-name | Compounded only | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | Transparent per-dose pricing with pay-as-you-go or membership options. | Anyone who wants a flat dose price and will check whether their state is one the GLP-1 program actually covers. |
| Desk Score | 63/100C | 81/100B− |
The verdict
Desk pick — Trellis VitalityTrellis Vitality takes this head-to-head with the higher Desk Score, 81/100 (B−) against 63/100 (C) for NP2GO. NP2GO still holds its ground where its strengths line up with yours.
Choose NP2GO if…
Transparent per-dose pricing with pay-as-you-go or membership options.
From $150/mo (lowest dose rung) sema · From $250/mo (lowest dose rung) tirz · 40 states
Choose Trellis Vitality if…
Anyone who wants a flat dose price and will check whether their state is one the GLP-1 program actually covers.
From $150/mo sema · From $199/mo tirz · All 50 states claimed; GLP-1 not offered in every state
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: NP2GO · Trellis Vitality.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- CoreAge Rx vs NP2GO
- CoreAge Rx vs Trellis Vitality
- NP2GO vs Ondra Health
- Ondra Health vs Trellis Vitality
- NP2GO vs Tyde Wellness
- Trellis Vitality vs Tyde Wellness
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.