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Head-to-head dispatch

Nolu vs Vaylen

Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.

Dispatch #73
Nolu

An all-in, LegitScript-verified GLP-1 line billed every 4 weeks rather than by the calendar month, with no named prescriber or pharmacy behind the price.

vs
Dispatch #2Desk pick
Vaylen

The strongest all-rounder among the newer entrants — low pricing, brand access, oral routes, and all 50 states on one account.

Vaylen takes this head-to-head with the higher Desk Score, 91/100 (A−) against 78/100 (C+) for Nolu. Nolu still holds its ground where its strengths line up with yours.

Desk Score, dimension by dimension

Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.

Nolu

78/100

C+

Overall

Vaylen

91/100

A−

Price transparency

70
88

State access

92
96

Molecule range

80
96

Onboarding speed

80
86

Support responsiveness

75
84

Licensing & trust

70
90

The spec sheet

FieldNoluVaylen
Semaglutide$249/mo injectable · $279/mo oral (billed per 4 weeks)$179/mo
Tirzepatide$339/mo injectable (billed per 4 weeks)$239/mo
CoverageAll 50 states + DCAll 50 states
Brand-nameCompounded onlyYes
Oral optionYesYes
Best forPatients who want one bundled per-order price and will budget for 13 billing cycles a year rather than 12.People who want maximum optionality — brand or compounded, oral or injectable — without giving up nationwide reach.
Desk Score78/100C+91/100A−

The verdict

Desk pick — Vaylen

Vaylen takes this head-to-head with the higher Desk Score, 91/100 (A−) against 78/100 (C+) for Nolu. Nolu still holds its ground where its strengths line up with yours.

Choose Nolu if…

Patients who want one bundled per-order price and will budget for 13 billing cycles a year rather than 12.

$249/mo injectable · $279/mo oral (billed per 4 weeks) sema · $339/mo injectable (billed per 4 weeks) tirz · All 50 states + DC

Choose Vaylen if…

People who want maximum optionality — brand or compounded, oral or injectable — without giving up nationwide reach.

$179/mo sema · $239/mo tirz · All 50 states

Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Nolu · Vaylen.

Also on the board

CoreAge Rx tops every dispatch at 94/100

Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.

More head-to-heads

Or see the full comparison hub and the complete board.

Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.