Head-to-head dispatch
NewSelf vs NextMeds
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo).
$100/mo (compounded) sema · $144/mo (compounded) tirz · Verified July 20, 2026
Marked down on: Not available in Mississippi and Louisiana
FDAWarning letter issued to NewSelf Limited dba NewSelf in February 2026. See the FDA warning-letter database.
Desk Score
NextMeds is a cash-pay telehealth membership that now publishes a full four-term ladder for both molecules, bundling the medication, telehealth visits, a 1:1 care coach and a registered nutritionist into one flat monthly price.
$79/mo month-to-month ($76/mo on the 3-month plan, $73/mo on the 6-month plan, $49/mo on the 12-month plan; compounded) sema · $109/mo month-to-month ($105/mo on the 3-month plan, $100/mo on the 6-month plan, $95/mo on the 12-month plan; compounded) tirz · Verified August 29, 2026
Marked down on: The page title, the banner and the closing panel all shout $49/mo and $95/mo — both are the 12-month rungs, and the month-to-month rates ($79 and $109) appear only on the card
NewSelf takes this head-to-head with the higher Desk Score, 79/100 (C+) against 71/100 (C) for NextMeds. NextMeds still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
NewSelf
79/100
C+
NextMeds
71/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | NewSelf | NextMeds |
|---|---|---|
| Semaglutide | $100/mo (compounded) | $79/mo month-to-month ($76/mo on the 3-month plan, $73/mo on the 6-month plan, $49/mo on the 12-month plan; compounded) |
| Tirzepatide | $144/mo (compounded) | $109/mo month-to-month ($105/mo on the 3-month plan, $100/mo on the 6-month plan, $95/mo on the 12-month plan; compounded) |
| Coverage | 49 states | All 50 states |
| Brand-name | Compounded only | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | Lowest-cost compounded GLP-1 with pharmacy quality transparency. | First-time patients who want an all-inclusive monthly price with coaching built in and no commitment — the $79 and $109 monthly rungs, not the advertised annual figures. |
| Desk Score | 79/100C+ | 71/100C |
The verdict
Desk pick — NewSelfNewSelf takes this head-to-head with the higher Desk Score, 79/100 (C+) against 71/100 (C) for NextMeds. NextMeds still holds its ground where its strengths line up with yours.
Choose NewSelf if…
Lowest-cost compounded GLP-1 with pharmacy quality transparency.
$100/mo (compounded) sema · $144/mo (compounded) tirz · 49 states
FDAWarning letter issued to NewSelf Limited dba NewSelf in February 2026. See the FDA warning-letter database.
Choose NextMeds if…
First-time patients who want an all-inclusive monthly price with coaching built in and no commitment — the $79 and $109 monthly rungs, not the advertised annual figures.
$79/mo month-to-month ($76/mo on the 3-month plan, $73/mo on the 6-month plan, $49/mo on the 12-month plan; compounded) sema · $109/mo month-to-month ($105/mo on the 3-month plan, $100/mo on the 6-month plan, $95/mo on the 12-month plan; compounded) tirz · All 50 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: NewSelf · NextMeds.
Also here
CoreAge Rx tops every dispatch at 94/100
Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: one price at every dose, both molecules, all 50 states — but the $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- CoreAge Rx vs NewSelf
- CoreAge Rx vs NextMeds
- NewSelf vs yourEra
- NextMeds vs yourEra
- NewSelf vs Sunlight
- NextMeds vs Sunlight
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.