Head-to-head dispatch
MyStart Health vs SkinnyRx
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
MyStart Health offers all-inclusive compounded semaglutide and tirzepatide at $299/month with a price-lock guarantee, same-day physician consultations, and 24/7 care team access.
Marked down on: Not BBB accredited — C+ rating with 10 complaints, mostly shipping delays and support access
FDAWarning letter issued to Matthew Stern, CEO MyStart Health LLC. in September 2025. See the FDA warning-letter database.
Desk Score
Both molecules by needle or by tablet, with the whole term ladder printed on the product page before any intake — and a headline rate that is the twelve-month rung, charged as one $2,388 payment on day one.
Marked down on: FDA issued Lean Rx, Inc. dba SkinnyRx a warning letter in February 2026; the letter is public in FDA's warning-letter database
FDAWarning letter issued to Lean Rx, Inc. dba SkinnyRx in February 2026. See the FDA warning-letter database.
SkinnyRx takes this head-to-head with the higher Desk Score, 78/100 (C+) against 70/100 (C) for MyStart Health. MyStart Health still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
MyStart Health
70/100
C
SkinnyRx
78/100
C+
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | MyStart Health | SkinnyRx |
|---|---|---|
| Semaglutide | $299/mo (all doses, compounded) | $349/mo month-to-month (compounded; the advertised rate is a 12-month prepay) |
| Tirzepatide | $299/mo (all doses, compounded) | $399/mo month-to-month (compounded; the advertised rate is a 12-month prepay) |
| Coverage | Coverage not published | 47 states + DC (not Alabama, Louisiana or Mississippi) |
| Brand-name | Compounded only | Compounded only |
| Oral option | Yes | Yes |
| Best for | Readers who want fastest compounded GLP-1 onboarding with a price lock. | Readers who want a tablet route on either molecule and can pay a year up front; anyone shopping month to month should compare $349 and $399, not the advertised $199 and $299. |
| Desk Score | 70/100C | 78/100C+ |
The verdict
Desk pick — SkinnyRxSkinnyRx takes this head-to-head with the higher Desk Score, 78/100 (C+) against 70/100 (C) for MyStart Health. MyStart Health still holds its ground where its strengths line up with yours.
Choose MyStart Health if…
Readers who want fastest compounded GLP-1 onboarding with a price lock.
$299/mo (all doses, compounded) sema · $299/mo (all doses, compounded) tirz · Coverage not published
FDAWarning letter issued to Matthew Stern, CEO MyStart Health LLC. in September 2025. See the FDA warning-letter database.
Choose SkinnyRx if…
Readers who want a tablet route on either molecule and can pay a year up front; anyone shopping month to month should compare $349 and $399, not the advertised $199 and $299.
$349/mo month-to-month (compounded; the advertised rate is a 12-month prepay) sema · $399/mo month-to-month (compounded; the advertised rate is a 12-month prepay) tirz · 47 states + DC (not Alabama, Louisiana or Mississippi)
FDAWarning letter issued to Lean Rx, Inc. dba SkinnyRx in February 2026. See the FDA warning-letter database.
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: MyStart Health · SkinnyRx.
Also here
CoreAge Rx tops every dispatch at 94/100
Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.
More head-to-heads
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- SkinnyRx vs Vytora Health
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.