Head-to-head comparison
MediRX vs PlushCare
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
MediRX is a telehealth weight-loss platform offering compounded GLP-1 injections — semaglutide starting at $149/month and tirzepatide starting at $199/month — plus NAD+ and a name-brand GLP-1 option.
$149/mo sema · $199/mo tirz · Verified July 2026
Marked down on: Doesn't publish the exact states it serves; telehealth rules vary by state
Desk Score
Established virtual primary-care telehealth platform (subsidiary of Transcarent, Inc., a Delaware corporation, alongside Accolade, 2nd.MD, and 98point6 by Transcarent).
From $149/mo (lowest dose rung) sema · From $399/mo (lowest dose rung) tirz · Verified July 2026
Marked down on: Facing a California class action alleging deceptive subscription enrollment and unauthorized charges after cancellation
PlushCare takes this head-to-head with the higher Desk Score, 73/100 (C) against 65/100 (C) for MediRX. MediRX still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
MediRX
65/100
C
PlushCare
73/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | MediRX | PlushCare |
|---|---|---|
| Semaglutide | $149/mo$149/mo (compounded) | From $149/molowest dose rung$149/mo (starting dose, compounded) |
| Tirzepatide | $199/mo$199/mo (compounded) | From $399/molowest dose rung$399/mo (starting dose, compounded) |
| Coverage | Not listed on MediRX's site (checked July 2026) | All 50 states |
| Brand-name | Yes | Yes |
| Oral option | Injectable only | Injectable only |
| Best for | People wanting LegitScript-certified compounded GLP-1 with low first-month promo pricing. | Virtual primary care that can also prescribe GLP-1s. |
| Desk Score | 65/100C | 73/100C |
The verdict
Desk pick — PlushCarePlushCare takes this head-to-head with the higher Desk Score, 73/100 (C) against 65/100 (C) for MediRX. MediRX still holds its ground where its strengths line up with yours.
Choose MediRX if…
People wanting LegitScript-certified compounded GLP-1 with low first-month promo pricing.
$149/mo sema · $199/mo tirz
Choose PlushCare if…
Virtual primary care that can also prescribe GLP-1s.
From $149/mo (lowest dose rung) sema · From $399/mo (lowest dose rung) tirz · All 50 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: MediRX · PlushCare.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- CoreAge Rx vs MediRX
- CoreAge Rx vs PlushCare
- MediRX vs Vytora Health
- PlushCare vs Vytora Health
- Effecty vs MediRX
- Effecty vs PlushCare
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.