Head-to-head comparison
MadeMed vs Tru2u
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
Publishes its price at every single dose, so what month six costs is knowable on day one.
$239/mo (3-month prepay) sema · $399/mo (3-month prepay) tirz · Verified August 2026
Marked down on: The most expensive tirzepatide here at $399/mo, and quarterly billing means the smallest charge on the site is $657 up front
Desk Score
Tru2u is a US direct-to-consumer telehealth and wellness store offering provider-guided compounded GLP-1 weight-loss therapy alongside hair, skincare, and supplement lines.
$225/mo sema · $345/mo tirz · Verified July 2026
Marked down on: No compounding pharmacy publicly named and no LegitScript seal shown
MadeMed takes this head-to-head with the higher Desk Score, 82/100 (B−) against 65/100 (C) for Tru2u. Tru2u still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
MadeMed
82/100
B−
Tru2u
65/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | MadeMed | Tru2u |
|---|---|---|
| Semaglutide | $239/mo3-month prepay$239/mo billed $717 every 3 months (from $199/mo on 6 months); sublingual tablets $219/mo billed $657 every 3 months (from $179/mo on 6 months) | $225/mo$225/mo |
| Tirzepatide | $399/mo3-month prepay$399/mo billed $1,197 every 3 months (from $369/mo on 6 months); sublingual tablets $299/mo billed $897 every 3 months (from $279/mo on 6 months) | $345/mo$345/mo |
| Coverage | 23 states | Not listed on Tru2u's site (checked July 2026) |
| Brand-name | Compounded only | Compounded only |
| Oral option | Yes | Yes |
| Best for | Anyone who expects to titrate and wants the eventual cost visible before starting. | Shoppers wanting compounded oral or injectable glp-1 options in one store. |
| Desk Score | 82/100B− | 65/100C |
The verdict
Desk pick — MadeMedMadeMed takes this head-to-head with the higher Desk Score, 82/100 (B−) against 65/100 (C) for Tru2u. Tru2u still holds its ground where its strengths line up with yours.
Choose MadeMed if…
Anyone who expects to titrate and wants the eventual cost visible before starting.
$239/mo (3-month prepay) sema · $399/mo (3-month prepay) tirz · 23 states
Choose Tru2u if…
Shoppers wanting compounded oral or injectable glp-1 options in one store.
$225/mo sema · $345/mo tirz
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: MadeMed · Tru2u.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- CoreAge Rx vs MadeMed
- CoreAge Rx vs Tru2u
- Fitish vs MadeMed
- Tru2u vs Vaylen
- MadeMed vs REMEVi
- Curex vs Tru2u
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.