Head-to-head dispatch
Luma Health Co vs Trillium Meds
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
Luma Health Co is a nurse-practitioner-led virtual weight-loss and wellness clinic founded by Tiffani McKnight, FNP-C.
Marked down on: Offers compounded retatrutide (labeled "RTT/GLP-3"), an investigational triple agonist not FDA-approved — a higher-risk, less-studied option
Desk Score
Trillium Meds is a small, owner-operated telehealth platform based in Portland, OR that connects patients with independent licensed providers and FDA-registered compounding pharmacies for compounded…
Marked down on: No labs, coaching, or clinical monitoring included — telehealth Rx and pharmacy fulfillment only
Trillium Meds takes this head-to-head with the higher Desk Score, 77/100 (C+) against 70/100 (C) for Luma Health Co. Luma Health Co still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Luma Health Co
70/100
C
Trillium Meds
77/100
C+
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Luma Health Co | Trillium Meds |
|---|---|---|
| Semaglutide | $120/mo (plus a separate fee, compounded) | $119/mo (3-month plan, compounded) |
| Tirzepatide | $180/mo (compounded) | $199/mo (3-month plan, compounded) |
| Coverage | 30 states | All 50 states |
| Brand-name | Compounded only | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | Readers who want no-subscription compounded GLP-1s, free follow-ups and consult discounts for first responders and teachers. | Readers who want legitScript-certified compounded GLP-1 telehealth, all 50 states + PR; sema $119/mo, tirz $199/mo (3-mo). |
| Desk Score | 70/100C | 77/100C+ |
The verdict
Desk pick — Trillium MedsTrillium Meds takes this head-to-head with the higher Desk Score, 77/100 (C+) against 70/100 (C) for Luma Health Co. Luma Health Co still holds its ground where its strengths line up with yours.
Choose Luma Health Co if…
Readers who want no-subscription compounded GLP-1s, free follow-ups and consult discounts for first responders and teachers.
$120/mo (plus a separate fee, compounded) sema · $180/mo (compounded) tirz · 30 states
Choose Trillium Meds if…
Readers who want legitScript-certified compounded GLP-1 telehealth, all 50 states + PR; sema $119/mo, tirz $199/mo (3-mo).
$119/mo (3-month plan, compounded) sema · $199/mo (3-month plan, compounded) tirz · All 50 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Luma Health Co · Trillium Meds.
Also here
CoreAge Rx tops every dispatch at 94/100
Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.
More head-to-heads
- Luma Health Co vs CoreAge Rx
- Trillium Meds vs Vaylen
- Luma Health Co vs Strut Health
- Trillium Meds vs Ondra Health
- Luma Health Co vs Invigor Medical
- Trillium Meds vs Vytora Health
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.