Head-to-head comparison
Luma Health Co vs Trillium Meds
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
Luma Health Co is a nurse-practitioner-led virtual weight-loss and wellness clinic founded by Tiffani McKnight, FNP-C.
$120/mo (+ membership fee) sema · $180/mo tirz · Verified July 2026
Marked down on: Offers compounded retatrutide (labeled "RTT/GLP-3"), an investigational triple agonist not FDA-approved — a higher-risk, less-studied option
Desk Score
Trillium Meds is a small, owner-operated telehealth platform based in Portland.
$119/mo (3-month prepay) sema · $199/mo (3-month prepay) tirz · Verified July 2026
Marked down on: No labs, coaching, or clinical monitoring included — telehealth Rx and pharmacy fulfillment only
Trillium Meds takes this head-to-head with the higher Desk Score, 77/100 (C+) against 70/100 (C) for Luma Health Co. Luma Health Co still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Luma Health Co
70/100
C
Trillium Meds
77/100
C+
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Luma Health Co | Trillium Meds |
|---|---|---|
| Semaglutide | $120/mo+ membership fee$120/mo (plus a separate fee, compounded) | $119/mo3-month prepay$119/mo (3-month plan, compounded) |
| Tirzepatide | $180/mo$180/mo (compounded) | $199/mo3-month prepay$199/mo (3-month plan, compounded) |
| Coverage | 30 states | All 50 states |
| Brand-name | Compounded only | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | No-subscription compounded GLP-1s, free follow-ups and consult discounts for first responders and teachers. | LegitScript-certified compounded GLP-1 telehealth, all 50 states + PR; sema $119/mo, tirz $199/mo (3-mo). |
| Desk Score | 70/100C | 77/100C+ |
The verdict
Desk pick — Trillium MedsTrillium Meds takes this head-to-head with the higher Desk Score, 77/100 (C+) against 70/100 (C) for Luma Health Co. Luma Health Co still holds its ground where its strengths line up with yours.
Choose Luma Health Co if…
No-subscription compounded GLP-1s, free follow-ups and consult discounts for first responders and teachers.
$120/mo (+ membership fee) sema · $180/mo tirz · 30 states
Choose Trillium Meds if…
LegitScript-certified compounded GLP-1 telehealth, all 50 states + PR; sema $119/mo, tirz $199/mo (3-mo).
$119/mo (3-month prepay) sema · $199/mo (3-month prepay) tirz · All 50 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: Luma Health Co · Trillium Meds.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
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Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.