Head-to-head comparison
Layla vs NuDay Rx
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
Layla is a US telehealth weight-loss program built around semaglutide, offering compounded semaglutide as injections and as oral dropper drops.
$237/mo sema · $199/mo tirz · Verified July 2026
Marked down on: Brand-inclusive GLP-1 program is expensive, starting around 1,299 dollars
Desk Score
NuDay Rx is a GLP-1 weight-loss telehealth service (on the CareValidate/careGLP platform) that pairs medication with video coaching and lifestyle support.
$249/mo sema · $329/mo tirz · Verified June 2026
Marked down on: Compounded semaglutide ($249) is pricier than some budget competitors
NuDay Rx takes this head-to-head with the higher Desk Score, 71/100 (C) against 70/100 (C) for Layla. Layla still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Layla
70/100
C
NuDay Rx
71/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Layla | NuDay Rx |
|---|---|---|
| Semaglutide | $237/mo$237/mo (all doses, compounded) | $249/mo$249/mo (compounded) |
| Tirzepatide | $199/mo$199/mo (all doses, compounded) | $329/mo$329/mo (compounded) |
| Coverage | Not listed on Layla's site (checked July 2026) | Not listed on NuDay Rx's site (checked June 2026) |
| Brand-name | Yes | Yes |
| Oral option | Yes | Yes |
| Best for | People wanting oral or injectable semaglutide with a brand-inclusive glp-1 upgrade path. | Shoppers wanting both compounded and brand GLP-1 options with coaching and a doctor consult. |
| Desk Score | 70/100C | 71/100C |
The verdict
Desk pick — NuDay RxNuDay Rx takes this head-to-head with the higher Desk Score, 71/100 (C) against 70/100 (C) for Layla. Layla still holds its ground where its strengths line up with yours.
Choose Layla if…
People wanting oral or injectable semaglutide with a brand-inclusive glp-1 upgrade path.
$237/mo sema · $199/mo tirz
Choose NuDay Rx if…
Shoppers wanting both compounded and brand GLP-1 options with coaching and a doctor consult.
$249/mo sema · $329/mo tirz
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: Layla · NuDay Rx.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- CoreAge Rx vs Layla
- CoreAge Rx vs NuDay Rx
- Layla vs RxSpan MD
- NuDay Rx vs RxSpan MD
- Layla vs Shed
- He & She MD vs NuDay Rx
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.