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Head-to-head dispatch

Knownwell vs Tyde Wellness

Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.

Dispatch #116
Knownwell

Knownwell is a weight-inclusive metabolic and primary care company co-founded by obesity-medicine specialist Dr.

vs
Dispatch #8Desk pick
Tyde Wellness

Low entry pricing, oral options, and 50-state reach — a strong value pick for first-time GLP-1 patients.

Tyde Wellness takes this head-to-head with the higher Desk Score, 89/100 (B+) against 71/100 (C) for Knownwell. Knownwell still holds its ground where its strengths line up with yours.

Desk Score, dimension by dimension

Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.

Knownwell

71/100

C

Overall

Tyde Wellness

89/100

B+

Price transparency

38
92

State access

86
96

Molecule range

77
92

Onboarding speed

78
85

Support responsiveness

93
83

Licensing & trust

80
88

The spec sheet

FieldKnownwellTyde Wellness
SemaglutideNot disclosed$149/mo
Tirzepatide$349/mo (brand Zepbound)$249/mo
CoverageAll 50 statesAll 50 states
Brand-nameYesCompounded only
Oral optionYesYes
Best forPatients wanting branded GLP-1s with obesity-medicine oversight and insurance options.First-timers who want an affordable, needle-optional on-ramp available anywhere in the country.
Desk Score71/100C89/100B+

The verdict

Desk pick — Tyde Wellness

Tyde Wellness takes this head-to-head with the higher Desk Score, 89/100 (B+) against 71/100 (C) for Knownwell. Knownwell still holds its ground where its strengths line up with yours.

Choose Knownwell if…

Patients wanting branded GLP-1s with obesity-medicine oversight and insurance options.

Not disclosed sema · $349/mo (brand Zepbound) tirz · All 50 states

Choose Tyde Wellness if…

First-timers who want an affordable, needle-optional on-ramp available anywhere in the country.

$149/mo sema · $249/mo tirz · All 50 states

Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Knownwell · Tyde Wellness.

Also on the board

CoreAge Rx tops every dispatch at 94/100

Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.

More head-to-heads

Or see the full comparison hub and the complete board.

Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.