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Head-to-head dispatch

Jyra Health vs TRYM Health

Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.

Dispatch #107Desk pick
Jyra Health

Jyra Health is an online weight-loss and longevity telehealth clinic offering compounded GLP-1 — semaglutide from $99/mo and tirzepatide from $133/mo (limited time) — prescribed by board-certified providers…

Marked down on: The $133/mo tirzepatide price is flagged 'limited time' — verify current pricing before enrolling

vs
Dispatch #188
TRYM Health

TRYM Health (TRYM) is a nationwide telehealth service offering compounded GLP-1 weight-loss medication — semaglutide (~$96/mo, $3.20/day) and tirzepatide (~$126/mo, $4.20/day) — as additive-free multi-dose…

Marked down on: Compounding pharmacy partner not named

FDAWarning letter issued to TRYM Health, Inc. dba TRYM Health in September 2025. See the FDA warning-letter database.

Jyra Health takes this head-to-head with the higher Desk Score, 75/100 (C) against 66/100 (C) for TRYM Health. TRYM Health still holds its ground where its strengths line up with yours.

Desk Score, dimension by dimension

Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.

Jyra Health

75/100

C

Overall

TRYM Health

66/100

C

Price transparency

66
94

State access

86
24

Molecule range

66
66

Onboarding speed

82
77

Support responsiveness

78
77

Licensing & trust

79
52

The spec sheet

FieldJyra HealthTRYM Health
Semaglutide$99/mo (starting dose, plus a separate fee, compounded)$96/mo (all doses, compounded)
Tirzepatide$133/mo (starting dose, promotional rate, compounded)$126/mo (all doses, compounded)
CoverageAll 50 statesCoverage not published
Brand-nameCompounded onlyCompounded only
Oral optionInjectable onlyInjectable only
Best forReaders who want budget shoppers wanting very low-cost compounded semaglutide or tirzepatide in any state.Readers who want budget-focused shoppers wanting low-cost compounded GLP-1 vials shipped nationwide.
Desk Score75/100C66/100C

The verdict

Desk pick — Jyra Health

Jyra Health takes this head-to-head with the higher Desk Score, 75/100 (C) against 66/100 (C) for TRYM Health. TRYM Health still holds its ground where its strengths line up with yours.

Choose Jyra Health if…

Readers who want budget shoppers wanting very low-cost compounded semaglutide or tirzepatide in any state.

$99/mo (starting dose, plus a separate fee, compounded) sema · $133/mo (starting dose, promotional rate, compounded) tirz · All 50 states

Choose TRYM Health if…

Readers who want budget-focused shoppers wanting low-cost compounded GLP-1 vials shipped nationwide.

$96/mo (all doses, compounded) sema · $126/mo (all doses, compounded) tirz · Coverage not published

FDAWarning letter issued to TRYM Health, Inc. dba TRYM Health in September 2025. See the FDA warning-letter database.

Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Jyra Health · TRYM Health.

Also here

CoreAge Rx tops every dispatch at 94/100

Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.

More head-to-heads

Or see the full comparison hub and the complete ranking.

Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.