Head-to-head dispatch
Jyra Health vs Sesame Care
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
Jyra Health is an online weight-loss and longevity telehealth clinic offering compounded GLP-1 — semaglutide from $99/mo and tirzepatide from $133/mo (limited time) — prescribed by board-certified providers…
Desk Score
An established national telehealth marketplace with the widest real brand-name GLP-1 access on the board — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency.
Sesame Care takes this head-to-head with the higher Desk Score, 87/100 (B+) against 75/100 (C) for Jyra Health. Jyra Health still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Jyra Health
75/100
C
Sesame Care
87/100
B+
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Jyra Health | Sesame Care |
|---|---|---|
| Semaglutide | $99/mo (starting dose, plus a separate fee, compounded) | From $149/mo (brand Wegovy pill) |
| Tirzepatide | $133/mo (starting dose, promotional rate, compounded) | Brand Zepbound (price varies) |
| Coverage | All 50 states | Nationwide marketplace |
| Brand-name | Compounded only | Yes |
| Oral option | Injectable only | Yes |
| Best for | Readers who want budget shoppers wanting very low-cost compounded semaglutide or tirzepatide in any state. | Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program. |
| Desk Score | 75/100C | 87/100B+ |
The verdict
Desk pick — Sesame CareSesame Care takes this head-to-head with the higher Desk Score, 87/100 (B+) against 75/100 (C) for Jyra Health. Jyra Health still holds its ground where its strengths line up with yours.
Choose Jyra Health if…
Readers who want budget shoppers wanting very low-cost compounded semaglutide or tirzepatide in any state.
$99/mo (starting dose, plus a separate fee, compounded) sema · $133/mo (starting dose, promotional rate, compounded) tirz · All 50 states
Choose Sesame Care if…
Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.
From $149/mo (brand Wegovy pill) sema · Brand Zepbound (price varies) tirz · Nationwide marketplace
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Jyra Health · Sesame Care.
Also on the board
CoreAge Rx tops every dispatch at 94/100
Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.
More head-to-heads
- Jyra Health vs CoreAge Rx
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- Jyra Health vs Strut Health
- Sesame Care vs Ondra Health
- Jyra Health vs Invigor Medical
- Sesame Care vs Vytora Health
Or see the full comparison hub and the complete board.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.