Head-to-head comparison
HealthSource vs SkyRx
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
HealthSource sells compounded semaglutide, compounded tirzepatide and a nightly sublingual tirzepatide tablet in all 50 states, charged every four weeks rather than by the calendar month.
$199 per 4 weeks sema · $299 per 4 weeks tirz · Verified August 2026
Marked down on: You pay before the medical intake — the questionnaire link appears only after checkout, and withdrawing once you have filled it in costs you $25–$45 for the provider review
Desk Score
SkyRx (sky-rx.co) is a US telehealth weight-loss program offering compounded semaglutide as an injection or oral drops, with compounded tirzepatide listed as coming soon.
$199/mo (12-month prepay) sema · Verified July 2026
Marked down on: 199 dollars pricing requires a 12-month subscription paid upfront
HealthSource takes this head-to-head with the higher Desk Score, 84/100 (B) against 63/100 (C) for SkyRx. SkyRx still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
HealthSource
84/100
B
SkyRx
63/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | HealthSource | SkyRx |
|---|---|---|
| Semaglutide | $199 per 4 weeks$199 every 4 weeks month-to-month (13 charges a year, all doses, compounded) | $199/mo12-month prepay$199/mo (all doses, 12-month plan, compounded) |
| Tirzepatide | $299 per 4 weeks$299 every 4 weeks month-to-month (13 charges a year, all doses, compounded) | Not listed on SkyRx's site (checked July 2026) |
| Coverage | All 50 states | Not listed on SkyRx's site (checked July 2026) |
| Brand-name | Compounded only | Compounded only |
| Oral option | Yes | Yes |
| Best for | Compounded semaglutide or tirzepatide, by weekly injection or as a nightly tablet, in all 50 states from $199 every four weeks. | Shoppers wanting all-inclusive compounded semaglutide with supplies included. |
| Desk Score | 84/100B | 63/100C |
The verdict
Desk pick — HealthSourceHealthSource takes this head-to-head with the higher Desk Score, 84/100 (B) against 63/100 (C) for SkyRx. SkyRx still holds its ground where its strengths line up with yours.
Choose HealthSource if…
Compounded semaglutide or tirzepatide, by weekly injection or as a nightly tablet, in all 50 states from $199 every four weeks.
$199 per 4 weeks sema · $299 per 4 weeks tirz · All 50 states
Choose SkyRx if…
Shoppers wanting all-inclusive compounded semaglutide with supplies included.
$199/mo (12-month prepay) sema
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: HealthSource · SkyRx.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- CoreAge Rx vs HealthSource
- CoreAge Rx vs SkyRx
- Curex vs HealthSource
- Curex vs SkyRx
- BetterMe Rx vs HealthSource
- Fitish vs SkyRx
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.