Head-to-head comparison
FMmeds vs Lyfe Rx
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
FMmeds is a Manhattan Beach-based DTC telehealth platform selling compounded semaglutide and tirzepatide co-formulated with vitamin B12, with no membership fee and a free initial visit billed only on approval.
$225/mo sema · $265/mo tirz · Verified July 2026
Marked down on: Compounded only — no FDA-approved Wegovy, Ozempic, Mounjaro, or Zepbound
Desk Score
Lyfe Rx offers compounded semaglutide ($289) and compounded tirzepatide ($399).
$225/mo sema · $299/mo tirz · Verified July 2026
Marked down on: No visible LegitScript or PCAB accreditation
FDAWarning letter issued to Lyfe Rx in September 2025. See the FDA warning-letter database.
FMmeds takes this head-to-head with the higher Desk Score, 81/100 (B−) against 62/100 (C) for Lyfe Rx. Lyfe Rx still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
FMmeds
81/100
B−
Lyfe Rx
62/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | FMmeds | Lyfe Rx |
|---|---|---|
| Semaglutide | $225/mo$225/mo (all doses, compounded) | $225/mo$225/mo (compounded) |
| Tirzepatide | $265/mo$265/mo (all doses, compounded) | $299/mo$299/mo (compounded) |
| Coverage | All 50 states | Not listed on Lyfe Rx's site (checked July 2026) |
| Brand-name | Compounded only | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | Flat-rate compounded GLP-1 co-formulated with vitamin B12, from $95/mo. | Readers comparing what GLP-1 programs publish before they commit. |
| Desk Score | 81/100B− | 62/100C |
The verdict
Desk pick — FMmedsFMmeds takes this head-to-head with the higher Desk Score, 81/100 (B−) against 62/100 (C) for Lyfe Rx. Lyfe Rx still holds its ground where its strengths line up with yours.
Choose FMmeds if…
Flat-rate compounded GLP-1 co-formulated with vitamin B12, from $95/mo.
$225/mo sema · $265/mo tirz · All 50 states
Choose Lyfe Rx if…
Readers comparing what GLP-1 programs publish before they commit.
$225/mo sema · $299/mo tirz
FDAWarning letter issued to Lyfe Rx in September 2025. See the FDA warning-letter database.
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: FMmeds · Lyfe Rx.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- CoreAge Rx vs FMmeds
- CoreAge Rx vs Lyfe Rx
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- Lyfe Rx vs Sesame Care
- FMmeds vs Peak Wellness
- Invigor Medical vs Lyfe Rx
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.