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Head-to-head dispatch

Defy Medical vs MadeMed

Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.

Dispatch #464
Defy Medical

Defy Medical is a long-running telehealth clinic, best known for hormone replacement, that also prescribes GLP-1 medications for weight loss.

Marked down on: GLP-1 pricing not published on the website

vs
Dispatch #14Desk pick
MadeMed

Publishes its price at every single dose, so what month six costs is knowable on day one.

Marked down on: The most expensive tirzepatide here at $399/mo quarterly

MadeMed takes this head-to-head with the higher Desk Score, 86/100 (B) against 46/100 (C) for Defy Medical. Defy Medical still holds its ground where its strengths line up with yours.

Desk Score, dimension by dimension

Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.

Defy Medical

46/100

C

Overall

MadeMed

86/100

B

Price transparency

20
95

State access

24
78

Molecule range

56
90

Onboarding speed

68
85

Support responsiveness

77
80

Licensing & trust

70
90

The spec sheet

FieldDefy MedicalMadeMed
SemaglutideNot disclosed$239/mo quarterly (from $199/mo on 6 months)
TirzepatideNot disclosed$399/mo quarterly (from $369/mo on 6 months)
CoverageCoverage not published40 states
Brand-nameCompounded onlyCompounded only
Oral optionYesYes
Best forPatients wanting GLP-1 in injection, ODT, or drop forms with thorough lab workups.Anyone who expects to titrate and wants the eventual cost visible before starting.
Desk Score46/100C86/100B

The verdict

Desk pick — MadeMed

MadeMed takes this head-to-head with the higher Desk Score, 86/100 (B) against 46/100 (C) for Defy Medical. Defy Medical still holds its ground where its strengths line up with yours.

Choose Defy Medical if…

Patients wanting GLP-1 in injection, ODT, or drop forms with thorough lab workups.

Not disclosed sema · Not disclosed tirz · Coverage not published

Choose MadeMed if…

Anyone who expects to titrate and wants the eventual cost visible before starting.

$239/mo quarterly (from $199/mo on 6 months) sema · $399/mo quarterly (from $369/mo on 6 months) tirz · 40 states

Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Defy Medical · MadeMed.

Also here

CoreAge Rx tops every dispatch at 94/100

Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.

More head-to-heads

Or see the full comparison hub and the complete ranking.

Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.