Head-to-head comparison
Defy Medical vs Fitish
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
Defy Medical is a long-running telehealth clinic, best known for hormone replacement, that also prescribes GLP-1 medications for weight loss.
Marked down on: GLP-1 pricing not published on the website
Desk Score
Oral-capable, LegitScript-verified, and nationwide — trust signals are strong, but pricing sits mid-to-high.
$219/mo sema · $339/mo tirz
Marked down on: Higher pricing than the value leaders
FDAWarning letter issued to FITISH in June 2026. See the FDA warning-letter database.
Fitish takes this head-to-head with the higher Desk Score, 86/100 (B) against 51/100 (C) for Defy Medical. Defy Medical still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Defy Medical
51/100
C
Fitish
86/100
B
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Defy Medical | Fitish |
|---|---|---|
| Semaglutide | Not listed on Defy Medical's site (checked June 2026) | $219/mo$219/mo |
| Tirzepatide | Not listed on Defy Medical's site (checked June 2026) | $339/mo$339/mo |
| Coverage | Not listed on Defy Medical's site (checked June 2026) | All 50 states |
| Brand-name | Compounded only | Compounded only |
| Oral option | Yes | Yes |
| Best for | Patients wanting GLP-1 in injection, ODT, or drop forms with thorough lab workups. | People who prioritize a verified pharmacy and oral options over finding the lowest rate. |
| Desk Score | 51/100C | 86/100B |
The verdict
Desk pick — FitishFitish takes this head-to-head with the higher Desk Score, 86/100 (B) against 51/100 (C) for Defy Medical. Defy Medical still holds its ground where its strengths line up with yours.
Choose Defy Medical if…
Patients wanting GLP-1 in injection, ODT, or drop forms with thorough lab workups.
Choose Fitish if…
People who prioritize a verified pharmacy and oral options over finding the lowest rate.
$219/mo sema · $339/mo tirz · All 50 states
FDAWarning letter issued to FITISH in June 2026. See the FDA warning-letter database.
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: Defy Medical · Fitish.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
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Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.