Head-to-head comparison
Clume Health vs Prime Doctor RX
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
Clume Health charges one figure, $259, for either molecule by either route, names four pharmacies with addresses, and advertises two homepage prices it does not sell.
From $259/mo sema · From $259/mo tirz · Verified September 2026
Marked down on: The homepage advertises $199 and $159 a month; the real figures are $259 and $219, and neither advertised number is sold.
Desk Score
The whole ladder is public and the asterisk is honest — but the billing cycle is 28 days and every price is labeled per month anyway.
$249 per 4 weeks sema · $339 per 4 weeks tirz · Verified September 2026
Marked down on: Its own arithmetic proves the 28-day cycle — $3,497 divided by thirteen is exactly $269, and nothing on the page divides cleanly by calendar months.
Clume Health takes this head-to-head with the higher Desk Score, 78/100 (C+) against 70/100 (C) for Prime Doctor RX. Prime Doctor RX still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Clume Health
78/100
C+
Prime Doctor RX
70/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Clume Health | Prime Doctor RX |
|---|---|---|
| Semaglutide | From $259/moFrom $259/mo (compounded) | $249 per 4 weeks$249 every 4 weeks (compounded — 13 charges a year, not 12) |
| Tirzepatide | From $259/moFrom $259/mo (compounded) | $339 per 4 weeks$339 every 4 weeks (compounded — 13 charges a year, not 12) |
| Coverage | All 50 states and D.C. claimed, no list published | Not listed on Prime Doctor RX's site (checked September 2026) |
| Brand-name | Compounded only | Compounded only |
| Oral option | Yes | Yes |
| Best for | Anyone who wants oral and injectable priced the same and the dispensing pharmacies named. | A buyer who will convert every figure into four-week cycles before comparing it to anything. |
| Desk Score | 78/100C+ | 70/100C |
The verdict
Desk pick — Clume HealthClume Health takes this head-to-head with the higher Desk Score, 78/100 (C+) against 70/100 (C) for Prime Doctor RX. Prime Doctor RX still holds its ground where its strengths line up with yours.
Choose Clume Health if…
Anyone who wants oral and injectable priced the same and the dispensing pharmacies named.
From $259/mo sema · From $259/mo tirz · All 50 states and D.C. claimed, no list published
Choose Prime Doctor RX if…
A buyer who will convert every figure into four-week cycles before comparing it to anything.
$249 per 4 weeks sema · $339 per 4 weeks tirz
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: Clume Health · Prime Doctor RX.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- Clume Health vs CoreAge Rx
- CoreAge Rx vs Prime Doctor RX
- Clume Health vs MadeMed
- MadeMed vs Prime Doctor RX
- Clume Health vs Nolu
- Nolu vs Prime Doctor RX
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.