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Head-to-head dispatch

Cielo vs Effecty

Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.

Dispatch #176
Cielo

Cielo is a compounded-GLP-1-only telehealth platform offering semaglutide and tirzepatide with no brand-name drugs and no TRT, hair, or mental-health add-ons — a focused, single-purpose alternative to…

Marked down on: No LegitScript, NABP .pharmacy, or HIPAA badge on the home page

vs
Dispatch #10Desk pick
Effecty

Below-market pricing with brand access across all 50 states — a clean, no-frills value option.

Marked down on: Injectable only — no oral route

Effecty takes this head-to-head with the higher Desk Score, 89/100 (B+) against 67/100 (C) for Cielo. Cielo still holds its ground where its strengths line up with yours.

Desk Score, dimension by dimension

Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.

Cielo

67/100

C

Overall

Effecty

89/100

B+

Price transparency

84
88

State access

24
96

Molecule range

79
90

Onboarding speed

72
84

Support responsiveness

77
82

Licensing & trust

68
90

The spec sheet

FieldCieloEffecty
Semaglutide$149/mo (all doses, compounded)$160/mo
Tirzepatide$249/mo (all doses, compounded)$240/mo
CoverageCoverage not publishedAll 50 states
Brand-nameYesYes
Oral optionInjectable onlyInjectable only
Best forReaders who want flat-rate compounded GLP-1 at the lowest 3-month bundle prices.Patients who want affordable brand-capable care nationwide without extra program layers.
Desk Score67/100C89/100B+

The verdict

Desk pick — Effecty

Effecty takes this head-to-head with the higher Desk Score, 89/100 (B+) against 67/100 (C) for Cielo. Cielo still holds its ground where its strengths line up with yours.

Choose Cielo if…

Readers who want flat-rate compounded GLP-1 at the lowest 3-month bundle prices.

$149/mo (all doses, compounded) sema · $249/mo (all doses, compounded) tirz · Coverage not published

Choose Effecty if…

Patients who want affordable brand-capable care nationwide without extra program layers.

$160/mo sema · $240/mo tirz · All 50 states

Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Cielo · Effecty.

Also here

CoreAge Rx tops every dispatch at 94/100

Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.

More head-to-heads

Or see the full comparison hub and the complete ranking.

Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.