Head-to-head comparison
Cielo vs Effecty
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
Cielo is a compounded-GLP-1-only telehealth platform offering semaglutide and tirzepatide with no brand-name drugs.
$149/mo sema · $249/mo tirz · Verified July 2026
Marked down on: No LegitScript, NABP.pharmacy, or HIPAA badge on the home page
Desk Score
Below-market pricing with brand access across all 50 states — a clean, no-frills value option.
$160/mo sema · $240/mo tirz
Marked down on: Injectable only — no oral route
Effecty takes this head-to-head with the higher Desk Score, 89/100 (B+) against 67/100 (C) for Cielo. Cielo still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Cielo
67/100
C
Effecty
89/100
B+
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Cielo | Effecty |
|---|---|---|
| Semaglutide | $149/mo$149/mo (all doses, compounded) | $160/mo$160/mo |
| Tirzepatide | $249/mo$249/mo (all doses, compounded) | $240/mo$240/mo |
| Coverage | Not listed on Cielo's site (checked July 2026) | All 50 states |
| Brand-name | Yes | Yes |
| Oral option | Injectable only | Injectable only |
| Best for | Flat-rate compounded GLP-1 at the lowest 3-month bundle prices. | Patients who want affordable brand-capable care nationwide without extra program layers. |
| Desk Score | 67/100C | 89/100B+ |
The verdict
Desk pick — EffectyEffecty takes this head-to-head with the higher Desk Score, 89/100 (B+) against 67/100 (C) for Cielo. Cielo still holds its ground where its strengths line up with yours.
Choose Cielo if…
Flat-rate compounded GLP-1 at the lowest 3-month bundle prices.
$149/mo sema · $249/mo tirz
Choose Effecty if…
Patients who want affordable brand-capable care nationwide without extra program layers.
$160/mo sema · $240/mo tirz · All 50 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: Cielo · Effecty.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- Cielo vs CoreAge Rx
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- Amazon One Medical vs Effecty
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.