Head-to-head comparison
Bionomy Health vs Optimized Health
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
Bionomy Health is a physician-led, direct-to-consumer men's telehealth service selling compounded GLP-1 weight-loss medication alongside testosterone, peptides and longevity protocols.
From $189/mo (lowest dose rung) sema · $249/mo tirz · Verified August 2026
Marked down on: The $189 is a starting rate, not a flat one: the page says 'From', the product card says 'Starter', and doses are titrated every four weeks with no published price for the dose you end up on
Desk Score
Verified and oral-capable, but availability is limited to five states — a narrow-reach specialist.
$200/mo sema · $250/mo tirz
Marked down on: Only five states served
Optimized Health takes this head-to-head with the higher Desk Score, 79/100 (C+) against 75/100 (C) for Bionomy Health. Bionomy Health still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Bionomy Health
75/100
C
Optimized Health
79/100
C+
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Bionomy Health | Optimized Health |
|---|---|---|
| Semaglutide | From $189/molowest dose rung$189/mo (starting dose, compounded) | $200/mo$200/mo |
| Tirzepatide | $249/mo$249/mo (compounded) | $250/mo$250/mo |
| Coverage | 48 states | MO, IA, KS, UT, WA |
| Brand-name | Compounded only | Compounded only |
| Oral option | Yes | Yes |
| Best for | Men seeking physician-led compounded glp-1 weight loss with trt and longevity add-ons. | Patients in MO, IA, KS, UT, or WA who want a verified, oral-capable program. |
| Desk Score | 75/100C | 79/100C+ |
The verdict
Desk pick — Optimized HealthOptimized Health takes this head-to-head with the higher Desk Score, 79/100 (C+) against 75/100 (C) for Bionomy Health. Bionomy Health still holds its ground where its strengths line up with yours.
Choose Bionomy Health if…
Men seeking physician-led compounded glp-1 weight loss with trt and longevity add-ons.
From $189/mo (lowest dose rung) sema · $249/mo tirz · 48 states
Choose Optimized Health if…
Patients in MO, IA, KS, UT, or WA who want a verified, oral-capable program.
$200/mo sema · $250/mo tirz · MO, IA, KS, UT, WA
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: Bionomy Health · Optimized Health.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
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Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.