Head-to-head comparison
Avono Health vs Clume Health
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
Fully online compounded GLP-1 telehealth with transparent, tiered pricing — microdose and standard semaglutide and tirzepatide in both injection and oral forms.
$269/mo sema · $349/mo tirz · Verified July 2026
Marked down on: Medications are compounded, not FDA-approved brand-name
Desk Score
Clume Health charges one figure, $259, for either molecule by either route, names four pharmacies with addresses, and advertises two homepage prices it does not sell.
From $259/mo sema · From $259/mo tirz · Verified September 2026
Marked down on: The homepage advertises $199 and $159 a month; the real figures are $259 and $219, and neither advertised number is sold.
Clume Health takes this head-to-head with the higher Desk Score, 78/100 (C+) against 63/100 (C) for Avono Health. Avono Health still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Avono Health
63/100
C
Clume Health
78/100
C+
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Avono Health | Clume Health |
|---|---|---|
| Semaglutide | $269/mo$269/mo (compounded) | From $259/moFrom $259/mo (compounded) |
| Tirzepatide | $349/mo$349/mo (compounded) | From $259/moFrom $259/mo (compounded) |
| Coverage | Not listed on Avono Health's site (checked July 2026) | All 50 states and D.C. claimed, no list published |
| Brand-name | Compounded only | Compounded only |
| Oral option | Yes | Yes |
| Best for | Shoppers who want a wide, transparently priced compounded GLP-1 menu including microdose and oral options. | Anyone who wants oral and injectable priced the same and the dispensing pharmacies named. |
| Desk Score | 63/100C | 78/100C+ |
The verdict
Desk pick — Clume HealthClume Health takes this head-to-head with the higher Desk Score, 78/100 (C+) against 63/100 (C) for Avono Health. Avono Health still holds its ground where its strengths line up with yours.
Choose Avono Health if…
Shoppers who want a wide, transparently priced compounded GLP-1 menu including microdose and oral options.
$269/mo sema · $349/mo tirz
Choose Clume Health if…
Anyone who wants oral and injectable priced the same and the dispensing pharmacies named.
From $259/mo sema · From $259/mo tirz · All 50 states and D.C. claimed, no list published
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: Avono Health · Clume Health.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
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- Clume Health vs Nolu
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.