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Head-to-head dispatch

Aspen vs Vyora Wellness

Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.

Dispatch #73Desk pick
Aspen

Aspen (Aspen Health Systems LLC) is a LegitScript-certified telehealth clinic offering compounded semaglutide and tirzepatide as physician-chosen weekly injections, with flat pricing at every dose.

Marked down on: Compounded semaglutide and tirzepatide only — no brand-name Wegovy, Zepbound or Ozempic — and compounded GLP-1s aren't FDA-reviewed or approved

vs
Dispatch #378
Vyora Wellness

Vyora Wellness offers compounded semaglutide ($299/mo) and compounded tirzepatide ($399/mo) as 4-week subscription plans.

Marked down on: State availability not publicly disclosed

Aspen takes this head-to-head with the higher Desk Score, 78/100 (C+) against 55/100 (C) for Vyora Wellness. Vyora Wellness still holds its ground where its strengths line up with yours.

Desk Score, dimension by dimension

Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.

Aspen

78/100

C+

Overall

Vyora Wellness

55/100

C

Price transparency

76
38

State access

86
24

Molecule range

66
72

Onboarding speed

80
70

Support responsiveness

75
82

Licensing & trust

85
79

The spec sheet

FieldAspenVyora Wellness
Semaglutide$279/mo (3-month plan, compounded)$299/mo (compounded)
Tirzepatide$399/mo (compounded)$399/mo (compounded)
CoverageAll 50 statesCoverage not published
Brand-nameCompounded onlyCompounded only
Oral optionInjectable onlyInjectable only
Best forReaders who want legitScript-certified compounded semaglutide/tirzepatide with a named accredited pharmacy and flat dosing.Patients wanting coaching-inclusive compounded GLP-1 programs.
Desk Score78/100C+55/100C

The verdict

Desk pick — Aspen

Aspen takes this head-to-head with the higher Desk Score, 78/100 (C+) against 55/100 (C) for Vyora Wellness. Vyora Wellness still holds its ground where its strengths line up with yours.

Choose Aspen if…

Readers who want legitScript-certified compounded semaglutide/tirzepatide with a named accredited pharmacy and flat dosing.

$279/mo (3-month plan, compounded) sema · $399/mo (compounded) tirz · All 50 states

Choose Vyora Wellness if…

Patients wanting coaching-inclusive compounded GLP-1 programs.

$299/mo (compounded) sema · $399/mo (compounded) tirz · Coverage not published

Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we file on a provider reads the same either way. Read full breakdowns: Aspen · Vyora Wellness.

Also here

CoreAge Rx tops every dispatch at 94/100

Whichever of these two you lean toward, the Desk's #1-rated provider outscores them both. The Desk's top dispatch: flat all-in pricing, both molecules, all 50 states — no teaser-rate traps.

More head-to-heads

Or see the full comparison hub and the complete ranking.

Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.