Head-to-head comparison
Ascend Medical vs Medsol RX
Two GLP-1 providers, one scorecard. Both are graded on the same six Desk Score dimensions — here is how they stack up, and which one fits you.
Desk Score
Ascend Medical is a virtual-first whole-person primary care practice whose Medical Weight Loss program prescribes semaglutide and tirzepatide alongside primary care, mental health, women's and men's health and diabetes care.
$225 (see conditions) sema · $240 (see conditions) tirz · Verified August 2026
Marked down on: Available only in Georgia and Texas
Desk Score
Medsol RX is a GLP-1 weight-loss telehealth program offering compounded semaglutide (from $209/mo) and tirzepatide, prescribed by board-certified clinicians via OpenLoop and shipped nationwide.
$209/mo sema · $250/mo tirz · Verified June 2026
Marked down on: Doesn't name its compounding pharmacy (generic 'certified U.S. pharmacies')
Medsol RX takes this head-to-head with the higher Desk Score, 76/100 (C) against 63/100 (C) for Ascend Medical. Ascend Medical still holds its ground where its strengths line up with yours.
Desk Score, dimension by dimension
Same six measured dimensions for both. The red flag marks the stronger side. See the methodology.
Ascend Medical
63/100
C
Medsol RX
76/100
C
Price transparency
State access
Molecule range
Onboarding speed
Support responsiveness
Licensing & trust
The spec sheet
| Field | Ascend Medical | Medsol RX |
|---|---|---|
| Semaglutide | $225see conditions$225 for the Starting Package; no billing period is published, and the page does not say whether the product is compounded or brand | $209/mo$209/mo (compounded) |
| Tirzepatide | $240see conditions$240 for the Starting Package; no billing period is published, and the page does not say whether the product is compounded or brand | $250/mo$250/mo (compounded) |
| Coverage | 2 states | All 50 states |
| Brand-name | Compounded only | Compounded only |
| Oral option | Injectable only | Injectable only |
| Best for | Georgia or Texas residents who want semaglutide or tirzepatide inside virtual primary care, with in-network insurance billing and a self-pay Starting Package at $225 and $240. | Shoppers who want flexible, HSA/FSA-eligible compounded GLP-1 plans with a care coach. |
| Desk Score | 63/100C | 76/100C |
The verdict
Desk pick — Medsol RXMedsol RX takes this head-to-head with the higher Desk Score, 76/100 (C) against 63/100 (C) for Ascend Medical. Ascend Medical still holds its ground where its strengths line up with yours.
Choose Ascend Medical if…
Georgia or Texas residents who want semaglutide or tirzepatide inside virtual primary care, with in-network insurance billing and a self-pay Starting Package at $225 and $240.
$225 (see conditions) sema · $240 (see conditions) tirz · 2 states
Choose Medsol RX if…
Shoppers who want flexible, HSA/FSA-eligible compounded GLP-1 plans with a care coach.
$209/mo sema · $250/mo tirz · All 50 states
Assume any provider we list may compensate us — we may earn a referral commission at no extra cost to you, and what we write about a provider reads the same either way. Read full breakdowns: Ascend Medical · Medsol RX.
Also here
CoreAge Rx leads the whole ranking at 94/100
Whichever of these two you lean toward, our #1-rated provider outscores them both. One price at every dose, both molecules, all 50 states. The $99 and $149 figures are 12-month plans paid up front, not a monthly bill.
More head-to-heads
- Ascend Medical vs CoreAge Rx
- CoreAge Rx vs Medsol RX
- Ascend Medical vs Invigor Medical
- HealthRX vs Medsol RX
- Ascend Medical vs Peak Wellness
- Invigor Medical vs Medsol RX
Or see the full comparison hub and the complete ranking.
Pricing and verification reflect each provider's public disclosures at last scoring; the Desk Score is our editorial judgment per the methodology. Prices change — confirm on each provider's own site. Not medical advice; see our disclosure.